| Player | Reason | From | Until | Days | Games missed |
|---|---|---|---|---|---|
 Emile Smith Rowe | Knock | 16 Oct 2026 | 27 Oct 2026 | 11 | 1 |
 Hugo Larsson | Groin Problems | 15 Oct 2026 | 23 Oct 2026 | 8 | 1 |
 Antonee Robinson | Ankle Injury | 8 Oct 2026 | 16 Oct 2026 | 8 | 1 |
 Kenny Tete | Concussion | 13 Sept 2026 | 25 Sept 2026 | 12 | 2 |
 Ryan Sessegnon | Groin Problems | 11 Sept 2026 | 19 Sept 2026 | 8 | 2 |
 Tom Cairney | Knee Surgery | 5 Aug 2026 | 9 Oct 2026 | 65 | 10 |
| Tom Cairney | Knee Surgery | 3 Aug 2026 | 16 Oct 2026 | 74 | 11 |
 Jonah Kusi-Asare | Knee Problems | 20 May 2026 | 25 May 2026 | 5 | 1 |
Unknown player | Knock | 8 May 2026 | 15 May 2026 | 7 | 1 |
 Sander Berge | Virus | 1 May 2026 | 4 May 2026 | 3 | 1 |
| Ryan Sessegnon | Hamstring Injury | 26 Apr 2026 | 18 May 2026 | 22 | 3 |
 Alex Iwobi | Hamstring Injury | 19 Apr 2026 | 15 May 2026 | 26 | 3 |
 Harrison Reed | Knee Bruise | 8 Apr 2026 | 17 Apr 2026 | 9 | 1 |
| Kenny Tete | Foot Injury | 16 Mar 2026 | 30 Apr 2026 | 45 | 4 |
| Emile Smith Rowe | Knock | 14 Mar 2026 | 20 Mar 2026 | 6 | 1 |
 Harry Wilson | Ankle Injury | 2 Mar 2026 | 14 Mar 2026 | 12 | 2 |
 Joachim Andersen | Cold | 28 Feb 2026 | 3 Mar 2026 | 3 | 1 |
 Kevin | Metatarsal Bruise | 23 Feb 2026 | 8 May 2026 | 74 | 9 |
| Antonee Robinson | Knock | 21 Feb 2026 | 28 Feb 2026 | 7 | 1 |
 Samuel Chukwueze | Calf Problems | 12 Feb 2026 | 28 Feb 2026 | 16 | 2 |
| Tom Cairney | Calf Problems | 6 Feb 2026 | 21 Feb 2026 | 15 | 3 |
 Saša Lukić | Hamstring Injury | 18 Jan 2026 | 3 Mar 2026 | 44 | 5 |
| Kenny Tete | Hamstring Injury | 2 Jan 2026 | 31 Jan 2026 | 29 | 2 |
 Josh King | Knee Problems | 28 Dec 2025 | 16 Jan 2026 | 19 | 3 |
| Jonah Kusi-Asare | Cold | 8 Dec 2025 | 14 Dec 2025 | 6 | 1 |
| Ryan Sessegnon | Hamstring Strain | 6 Dec 2025 | 6 Jan 2026 | 31 | 2 |
 Rodrigo Muniz | Hamstring Injury | 15 Nov 2025 | 6 Feb 2026 | 83 | 15 |
 Issa Diop | Knock | 31 Oct 2025 | 28 Nov 2025 | 28 | 3 |
| Emile Smith Rowe | Hamstring Injury | 26 Oct 2025 | 31 Oct 2025 | 5 | 1 |
| Joachim Andersen | Muscle Injury | 19 Oct 2025 | 31 Oct 2025 | 12 | 2 |
| Harry Wilson | Knock | 19 Oct 2025 | 31 Oct 2025 | 12 | 2 |
| Antonee Robinson | Knee Problems | 17 Oct 2025 | 12 Dec 2025 | 56 | 8 |
| Samuel Chukwueze | Calf Injury | 15 Oct 2025 | 31 Oct 2025 | 16 | 3 |
| Saša Lukić | Groin Injury | 4 Oct 2025 | 24 Oct 2025 | 20 | 1 |
Unknown player | Hip Injury | 29 Sept 2025 | 17 Oct 2025 | 18 | 1 |
| Rodrigo Muniz | Muscle Injury | 27 Sept 2025 | 31 Oct 2025 | 34 | 5 |
| Kenny Tete | Knee Injury | 27 Sept 2025 | 17 Oct 2025 | 20 | 2 |
| Issa Diop | Knock | 19 Sept 2025 | 29 Sept 2025 | 10 | 2 |
| Antonee Robinson | Knee Problems | 19 Sept 2025 | 22 Sept 2025 | 3 | 1 |
| Harrison Reed | Knock | 12 Sept 2025 | 22 Sept 2025 | 10 | 2 |
| Antonee Robinson | Rest | 25 Aug 2025 | 29 Aug 2025 | 4 | 1 |
| Issa Diop | Knock | 22 Aug 2025 | 1 Sept 2025 | 10 | 3 |
| Ryan Sessegnon | Minor Knock | 10 Aug 2025 | 18 Aug 2025 | 8 | 1 |
| Kevin | Meniscus Injury | 2 Aug 2025 | — | — | 66 |
| Antonee Robinson | Knee Surgery | 27 May 2025 | 23 Aug 2025 | 88 | 0 |
 Timothy Castagne | Ankle Surgery | 7 May 2025 | 15 Jul 2025 | 69 | 3 |
| Antonee Robinson | Knock | 5 May 2025 | 17 May 2025 | 12 | 1 |
| Saša Lukić | Knock | 5 May 2025 | 16 May 2025 | 11 | 1 |
| Harrison Reed | Calf Injury | 4 May 2025 | 1 Jun 2025 | 28 | 3 |
| Antonee Robinson | Knock | 25 Apr 2025 | 2 May 2025 | 7 | 1 |
| Emile Smith Rowe | Minor Knock | 18 Apr 2025 | 24 Apr 2025 | 6 | 1 |
| Rodrigo Muniz | Achilles Tendon Problems | 15 Apr 2025 | 1 Jun 2025 | 47 | 6 |
| Issa Diop | Injury | 6 Apr 2025 | 3 May 2025 | 27 | 4 |
 Adama Traoré | Knock | 3 Mar 2025 | 14 Mar 2025 | 11 | 1 |
| Emile Smith Rowe | Ankle Injury | 23 Feb 2025 | 1 Mar 2025 | 6 | 1 |
| Harry Wilson | Broken Foot | 27 Jan 2025 | 18 Apr 2025 | 81 | 11 |
| Harrison Reed | Fitness | 1 Jan 2025 | 8 Jan 2025 | 7 | 1 |
| Sander Berge | Ankle Injury | 23 Dec 2024 | 17 Jan 2025 | 25 | 2 |
| Emile Smith Rowe | Bruise | 16 Dec 2024 | 28 Dec 2024 | 12 | 2 |
| Kenny Tete | Knee Injury | 15 Dec 2024 | 6 Apr 2025 | 112 | 18 |
Unknown player | Hamstring Injury | 6 Dec 2024 | 1 Jun 2025 | 177 | 10 |
 Jorge Cuenca | Knock | 27 Nov 2024 | 4 Dec 2024 | 7 | 1 |
| Joachim Andersen | Achilles Tendon Problems | 24 Nov 2024 | 19 Dec 2024 | 25 | 4 |
| Harrison Reed | Knee Surgery | 21 Nov 2024 | 31 Dec 2024 | 40 | 8 |
| Timothy Castagne | Hamstring Injury | 14 Oct 2024 | 3 Nov 2024 | 20 | 2 |
| Saša Lukić | Shoulder Injury | 12 Oct 2024 | 22 Nov 2024 | 41 | 4 |
| Jorge Cuenca | Ankle Injury | 26 Sept 2024 | 18 Oct 2024 | 22 | 2 |
Unknown player | Calf Injury | 9 Sept 2024 | 18 Oct 2024 | 39 | 3 |
| Saša Lukić | Calf Injury | 9 May 2024 | 20 May 2024 | 11 | 1 |
| Issa Diop | Calf Problems | 2 Mar 2024 | 6 Apr 2024 | 35 | 5 |
Unknown player | Cold | 16 Feb 2024 | 19 Feb 2024 | 3 | 1 |
| Kenny Tete | Achilles Tendon Problems | 9 Feb 2024 | 19 Feb 2024 | 10 | 2 |
 Tosin Adarabioyo | Knock | 4 Feb 2024 | 16 Feb 2024 | 12 | 1 |
| Issa Diop | Hamstring Injury | 31 Jan 2024 | 9 Feb 2024 | 9 | 1 |
Unknown player | Hamstring Injury | 31 Jan 2024 | 14 Mar 2024 | 43 | 5 |
| Harry Wilson | Shoulder Injury | 27 Jan 2024 | 9 Feb 2024 | 13 | 3 |
Unknown player | Hamstring Injury | 20 Dec 2023 | 30 Dec 2023 | 10 | 2 |
 Calvin Bassey | Cold | 15 Dec 2023 | 18 Dec 2023 | 3 | 1 |
Unknown player | Calf Injury | 6 Dec 2023 | 9 Jan 2024 | 34 | 8 |
Unknown player | Knock | 23 Nov 2023 | 30 Dec 2023 | 37 | 8 |
| Adama Traoré | Hamstring Injury | 20 Nov 2023 | 9 Feb 2024 | 81 | 16 |
| Rodrigo Muniz | Knee Injury | 5 Nov 2023 | 9 Dec 2023 | 34 | 4 |
Unknown player | Minor Knock | 28 Oct 2023 | 31 Oct 2023 | 3 | 1 |
| Issa Diop | Foot Injury | 8 Oct 2023 | 15 Dec 2023 | 68 | 5 |
| Kenny Tete | Groin Problems | 17 Sept 2023 | 11 Nov 2023 | 55 | 5 |
| Adama Traoré | Hamstring Injury | 11 Sept 2023 | 11 Nov 2023 | 61 | 6 |
| Antonee Robinson | Muscular Problems | 10 Sept 2023 | 22 Sept 2023 | 12 | 1 |
| Tosin Adarabioyo | Groin Surgery | 31 Aug 2023 | 26 Nov 2023 | 87 | 10 |
| Saša Lukić | Knee Injury | 27 Aug 2023 | 1 Oct 2023 | 35 | 5 |
Unknown player | Achilles Tendon Problems | 24 Aug 2023 | 1 Sept 2023 | 8 | 2 |
Unknown player | Acromioclavicular Joint Dislocation | 23 Jul 2023 | 16 Aug 2023 | 24 | 5 |
 Daniel James | Hamstring Injury | 7 May 2023 | 21 May 2023 | 14 | 2 |
Unknown player | Broken Arm | 30 Apr 2023 | 29 May 2023 | 29 | 5 |
Unknown player | Ankle Injury | 30 Apr 2023 | 29 May 2023 | 29 | 5 |
Unknown player | Muscle Tear | 25 Apr 2023 | 2 May 2023 | 7 | 2 |
Unknown player | Thigh Problems | 10 Mar 2023 | 13 Mar 2023 | 3 | 0 |
Unknown player | Injury | 5 Mar 2023 | 13 Mar 2023 | 8 | 1 |
Unknown player | Collateral Ligament Tear | 27 Feb 2023 | 30 Jun 2023 | 123 | — |
Unknown player | Knock | 15 Feb 2023 | 28 Feb 2023 | 13 | 1 |
| Tom Cairney | Ankle Injury | 8 Feb 2023 | 18 Mar 2023 | 38 | 7 |
