| Player | Reason | From | Until | Days | Games missed |
|---|---|---|---|---|---|
 Troy Parrott | Injury | 14 Aug 2026 | 24 Aug 2026 | 10 | 2 |
 Unknown player | Muscle Injury | 11 Aug 2026 | 11 Sept 2026 | 31 | 6 |
 Diego Conde | Shoulder Injury | 27 Jul 2026 | 31 Aug 2026 | 35 | 8 |
 Unknown player | Fitness | 19 May 2026 | 25 May 2026 | 6 | 1 |
 Aitor Ruibal | Meniscus Injury | 16 May 2026 | 14 Sept 2026 | 121 | 2 |
 Unknown player | Calf Injury | 13 May 2026 | 31 May 2026 | 18 | 2 |
 Junior Firpo | Muscle Injury | 1 Apr 2026 | 1 May 2026 | 30 | 6 |
| Unknown player | Ankle Surgery | 19 Jan 2026 | 11 Mar 2026 | 51 | 10 |
 Rodrigo Riquelme | Adductor Injury | 19 Jan 2026 | 2 Feb 2026 | 14 | 3 |
 Giovani Lo Celso | Hamstring Injury | 17 Jan 2026 | 5 Apr 2026 | 78 | 16 |
 Cucho Hernández | Hamstring Injury | 10 Jan 2026 | 10 Feb 2026 | 31 | 9 |
| Junior Firpo | Hamstring Injury | 10 Jan 2026 | 5 Feb 2026 | 26 | 7 |
 Diego Llorente | Adductor Injury | 15 Dec 2025 | 1 Jan 2026 | 17 | 5 |
| Junior Firpo | Hamstring Injury | 6 Dec 2025 | 1 Jan 2026 | 26 | 5 |
 Isco | Ankle Injury | 27 Nov 2025 | 13 Apr 2026 | 137 | 29 |
| Unknown player | Leg Injury | 27 Nov 2025 | 19 Dec 2025 | 22 | 6 |
| Unknown player | Stomach Flu | 22 Nov 2025 | 25 Nov 2025 | 3 | 1 |
 Unknown player | Muscle Tear | 2 Nov 2025 | 1 Dec 2025 | 29 | 5 |
| Junior Firpo | Hamstring Injury | 30 Oct 2025 | 15 Nov 2025 | 16 | 4 |
| Unknown player | Muscle Injury | 3 Oct 2025 | 7 Oct 2025 | 4 | 1 |
| Isco | Broken Fibula | 10 Aug 2025 | 23 Nov 2025 | 105 | 16 |
 Nelson Deossa | Ankle Injury | 4 Aug 2025 | 27 Aug 2025 | 23 | 3 |
 Abde Ezzalzouli | Injury | 3 Jun 2025 | 10 Sept 2025 | 99 | 5 |
| Giovani Lo Celso | Muscular Problems | 19 May 2025 | 11 Aug 2025 | 84 | 3 |
| Diego Llorente | Hamstring Injury | 13 Apr 2025 | 30 Jun 2025 | 78 | 12 |
| Abde Ezzalzouli | Ankle Injury | 25 Mar 2025 | 11 Apr 2025 | 17 | 2 |
 Johnny Cardoso | Muscle Injury | 10 Mar 2025 | 15 Mar 2025 | 5 | 1 |
| Abde Ezzalzouli | Foot Bruise | 21 Feb 2025 | 3 Mar 2025 | 10 | 2 |
 Marc Roca | Foot Injury | 17 Feb 2025 | 26 Aug 2025 | 190 | 25 |
 Ángel Ortiz | Ankle Sprain | 16 Feb 2025 | 3 Mar 2025 | 15 | 2 |
| Giovani Lo Celso | Muscle Injury | 16 Feb 2025 | 25 Mar 2025 | 37 | 8 |
 Héctor Bellerín | Doubtful | 25 Jan 2025 | 25 Jan 2025 | 0 | 1 |
 Unknown player | Doubtful | 25 Jan 2025 | 25 Jan 2025 | 0 | 1 |
 Pablo Fornals | Doubtful | 25 Jan 2025 | 25 Jan 2025 | 0 | 1 |
 Unknown player | Muscle Injury | 21 Jan 2025 | 10 Feb 2025 | 20 | 3 |
| Pablo Fornals | Muscle Strain | 20 Jan 2025 | 25 Feb 2025 | 36 | 7 |
| Giovani Lo Celso | Adductor Injury | 12 Jan 2025 | 1 Feb 2025 | 20 | 3 |
| Unknown player | Knee Injury | 16 Dec 2024 | 3 Feb 2025 | 49 | 7 |
 Nobel Mendy | Injury | 23 Nov 2024 | 23 Nov 2024 | 0 | 0 |
| Pablo Fornals | Muscle Injury | 20 Nov 2024 | 18 Dec 2024 | 28 | 7 |
| Johnny Cardoso | Muscle Injury | 15 Nov 2024 | 10 Dec 2024 | 25 | 5 |
| Héctor Bellerín | Inflammation Of Pubic Bone | 4 Nov 2024 | 1 Mar 2025 | 117 | 22 |
| Giovani Lo Celso | Hamstring Injury | 17 Oct 2024 | 18 Nov 2024 | 32 | 6 |
| Marc Roca | Ankle Injury | 15 Oct 2024 | 15 Jan 2025 | 92 | 18 |
 Unknown player | Bruise On Ankle | 25 Sept 2024 | 27 Sept 2024 | 2 | 1 |
| Unknown player | Leg Injury | 24 Sept 2024 | 16 Oct 2024 | 22 | 4 |
 Unknown player | Achilles Heel Problems | 13 Sept 2024 | 13 Mar 2025 | 181 | 37 |
| Isco | Broken Fibula | 6 Sept 2024 | 6 Dec 2024 | 91 | 18 |
| Nobel Mendy | Injury | 25 Aug 2024 | 26 Aug 2024 | 1 | 0 |
 Marc Bartra | Muscle Strain | 25 Aug 2024 | 1 Oct 2024 | 37 | 8 |
 Unknown player | Knee Injury | 19 May 2024 | 19 Aug 2024 | 92 | 17 |
| Isco | Broken Fibula | 17 May 2024 | 5 Sept 2024 | 111 | 9 |
 Unknown player | Injury | 28 Apr 2024 | 15 Sept 2024 | 140 | 18 |
| Unknown player | Hamstring Injury | 31 Mar 2024 | 31 May 2024 | 61 | 9 |
| Unknown player | Muscle Injury | 25 Feb 2024 | 17 Mar 2024 | 21 | 3 |
 Unknown player | Broken Nose Bone | 24 Feb 2024 | 8 Mar 2024 | 13 | 2 |
| Unknown player | Injury | 15 Feb 2024 | 19 Feb 2024 | 4 | 1 |
 Abner | Ankle Sprain | 4 Feb 2024 | 25 Feb 2024 | 21 | 4 |
| Isco | Torn Muscle Bundle | 4 Feb 2024 | 24 Mar 2024 | 49 | 9 |
 Ayoze Pérez | Ankle Injury | 18 Jan 2024 | 1 Mar 2024 | 43 | 8 |
| Unknown player | Calf Injury | 15 Jan 2024 | 12 Feb 2024 | 28 | 2 |
| Unknown player | Hamstring Injury | 10 Jan 2024 | 2 Feb 2024 | 23 | 3 |
 Guido Rodríguez | Ankle Injury | 9 Dec 2023 | 11 Mar 2024 | 93 | 16 |
 Unknown player | Injury | 7 Dec 2023 | 9 Dec 2023 | 2 | 0 |
| Unknown player | Inflammation Of The Biceps Tendon In The Thigh | 27 Nov 2023 | 14 Dec 2023 | 17 | 4 |
 Unknown player | Hamstring Injury | 12 Nov 2023 | 5 Feb 2024 | 85 | 12 |
 Unknown player | Cruciate Ligament Tear | 24 Oct 2023 | 24 May 2024 | 213 | — |
| Marc Bartra | Achilles Tendon Problems | 9 Oct 2023 | 6 Mar 2024 | 149 | 20 |
 Unknown player | Injury | 26 Sept 2023 | 16 Oct 2023 | 20 | 4 |
 Unknown player | Injury | 24 Sept 2023 | 3 Oct 2023 | 9 | 3 |
| Unknown player | Muscle Injury | 13 Sept 2023 | 1 Jan 2024 | 110 | 11 |
| Unknown player | Knee Injury | 15 Aug 2023 | 30 Oct 2023 | 76 | 14 |
| Unknown player | Muscle Injury | 1 Aug 2023 | 25 Sept 2023 | 55 | 8 |
 Raúl García | Injury | 4 Jul 2023 | 10 Aug 2023 | 37 | 6 |
 Unknown player | Doubtful | 4 Jun 2023 | 4 Jun 2023 | 0 | 1 |
 Unknown player | Injury | 26 May 2023 | 8 Jul 2023 | 43 | 2 |
| Unknown player | Minor Knock | 22 May 2023 | 26 May 2023 | 4 | 1 |
| Unknown player | Ankle Injury | 1 Apr 2023 | 1 May 2023 | 30 | 6 |
| Abner | Doubtful | 19 Mar 2023 | 19 Mar 2023 | 0 | 1 |
| Abner | Hamstring Injury | 17 Mar 2023 | 31 Mar 2023 | 14 | 1 |
| Unknown player | Cruciate Ligament Tear | 27 Feb 2023 | 17 Sept 2023 | 202 | 27 |
 Juan Cruz | Muscle Injury | 5 Feb 2023 | 2 Apr 2023 | 56 | 8 |
 Paul Akouokou | Appendicitis | 4 Feb 2023 | 20 Feb 2023 | 16 | 3 |
| Unknown player | Muscle Injury | 16 Jan 2023 | 25 Jan 2023 | 9 | 2 |
| Juan Cruz | Muscle Injury | 30 Nov 2022 | 16 Jan 2023 | 47 | — |
 Juanmi | Torn Ankle Ligaments | 9 Sept 2022 | 27 Dec 2022 | 109 | 21 |
| Unknown player | Calf Muscle Tear | 3 Sept 2022 | 1 Oct 2022 | 28 | 5 |
| Unknown player | Ankle Injury | 27 Aug 2022 | 6 Sept 2022 | 10 | 1 |
 Sergio Canales | Injury | 14 Aug 2022 | 23 Aug 2022 | 9 | 2 |
| Unknown player | Minor Knock | 25 Apr 2022 | 5 May 2022 | 10 | 1 |
| Unknown player | Doubtful | 6 Mar 2022 | 6 Mar 2022 | 0 | 1 |
| Unknown player | Calf Injury | 28 Jan 2022 | 21 Feb 2022 | 24 | 5 |
 Unknown player | Muscle Injury | 17 Jan 2022 | 20 Jan 2022 | 3 | 1 |
 Unknown player | Achilles Tendon Problems | 4 Jan 2022 | 1 Sept 2022 | 240 | 38 |
| Unknown player | Torn Muscle Fiber | 4 Jan 2022 | 17 Jan 2022 | 13 | 2 |
 Juan Miranda | Muscle Injury | 20 Dec 2021 | 10 Jan 2022 | 21 | 2 |
 Unknown player | Muscle Injury | 17 Dec 2021 | 3 Jan 2022 | 17 | 1 |
| Unknown player | Muscle Injury | 19 Sept 2021 | 19 Oct 2021 | 30 | 5 |
| Juan Miranda | Knee Problems | 17 Sept 2021 | 21 Sept 2021 | 4 | 1 |
| Marc Bartra | Muscle Injury | 14 Sept 2021 | 24 Sept 2021 | 10 | 2 |
