| Player | Reason | From | Until | Days | Games missed |
|---|---|---|---|---|---|
 Unknown player | Knee Injury | 14 Jan 2018 | 11 Feb 2018 | 28 | 6 |
 Gabriel Jesus | Torn Knee Ligaments | 1 Jan 2018 | 24 Feb 2018 | 54 | 12 |
 Phil Foden | Foot Injury | 21 Dec 2017 | 9 Feb 2018 | 50 | 12 |
 Unknown player | Cold | 27 Nov 2017 | 4 Dec 2017 | 7 | 1 |
 John Stones | Hamstring Injury | 20 Nov 2017 | 1 Jan 2018 | 42 | 11 |
 Unknown player | Rib Fracture | 28 Sept 2017 | 14 Oct 2017 | 16 | 1 |
 Unknown player | Cruciate Ligament Tear | 25 Sept 2017 | 11 Apr 2018 | 198 | 42 |
| Unknown player | Hamstring Strain | 24 Jul 2017 | 24 Aug 2017 | 31 | 6 |
 Unknown player | Calf Muscle Tear | 27 Apr 2017 | 23 Jun 2017 | 57 | 6 |
| Gabriel Jesus | Metatarsal Fracture | 16 Feb 2017 | 24 Apr 2017 | 67 | 12 |
 Unknown player | Back Injury | 9 Feb 2017 | 1 Mar 2017 | 20 | 3 |
| Unknown player | Muscle Injury | 15 Dec 2016 | 16 Jan 2017 | 32 | 5 |
 Unknown player | Cruciate Ligament Tear | 15 Dec 2016 | 13 Aug 2017 | 241 | 34 |
 Kevin De Bruyne | Calf Injury | 23 Oct 2016 | 28 Oct 2016 | 5 | 2 |
| Kevin De Bruyne | Hamstring Injury | 25 Sept 2016 | 14 Oct 2016 | 19 | 2 |
| Unknown player | Muscle Injury | 1 Sept 2016 | 5 Jan 2017 | 126 | 25 |
| Unknown player | Muscular Problems | 29 Aug 2016 | 12 Sept 2016 | 14 | 1 |
| Unknown player | Hamstring Injury | 4 Aug 2016 | 5 Sept 2016 | 32 | 6 |
 Unknown player | Knock | 28 Apr 2016 | 29 May 2016 | 31 | 4 |
| Unknown player | Back Problems | 18 Apr 2016 | 21 Apr 2016 | 3 | 1 |
| Unknown player | Ankle Injury | 14 Apr 2016 | 21 Apr 2016 | 7 | 2 |
| Unknown player | Ankle Problems | 7 Apr 2016 | 11 Apr 2016 | 4 | 1 |
 Unknown player | Calf Injury | 21 Mar 2016 | 4 Apr 2016 | 14 | 1 |
 Unknown player | Groin Injury | 21 Mar 2016 | 18 Apr 2016 | 28 | 5 |
 Unknown player | Ankle Problems | 17 Mar 2016 | 24 Mar 2016 | 7 | 1 |
| Unknown player | Minor Knock | 18 Feb 2016 | 22 Feb 2016 | 4 | 1 |
| Unknown player | Achilles Tendon Problems | 11 Feb 2016 | 4 Apr 2016 | 53 | 10 |
 Unknown player | Hamstring Injury | 2 Feb 2016 | 26 Feb 2016 | 24 | 5 |
| Kevin De Bruyne | Knee Injury | 28 Jan 2016 | 31 Mar 2016 | 63 | 12 |
 Unknown player | Knock | 7 Jan 2016 | 21 Jan 2016 | 14 | 3 |
| Unknown player | Rest | 7 Jan 2016 | 11 Jan 2016 | 4 | 1 |
 Unknown player | Hamstring Injury | 6 Jan 2016 | 24 Feb 2016 | 49 | 11 |
 Unknown player | Calf Injury | 4 Jan 2016 | 26 Feb 2016 | 53 | 12 |
| Unknown player | Minor Knock | 28 Dec 2015 | 4 Jan 2016 | 7 | 2 |
 Unknown player | Injury | 13 Dec 2015 | 6 Feb 2016 | 55 | 4 |
 Unknown player | Hamstring Injury | 7 Dec 2015 | 28 Dec 2015 | 21 | 4 |
| Unknown player | Knock | 30 Nov 2015 | 14 Dec 2015 | 14 | 4 |
| Unknown player | Thigh Problems | 26 Nov 2015 | 3 Dec 2015 | 7 | 2 |
| Unknown player | Knock | 9 Nov 2015 | 27 Nov 2015 | 18 | 2 |
| Unknown player | Hamstring Injury | 12 Oct 2015 | 19 Nov 2015 | 38 | 7 |
| Unknown player | Ankle Sprain | 12 Oct 2015 | 26 Nov 2015 | 45 | 9 |
| Unknown player | Muscle Injury | 19 Sept 2015 | 1 Oct 2015 | 12 | 3 |
 Unknown player | Hip Bruise | 19 Sept 2015 | 28 Sept 2015 | 9 | 3 |
| Unknown player | Minor Knock | 17 Sept 2015 | 28 Sept 2015 | 11 | 3 |
| Unknown player | Minor Knock | 10 Sept 2015 | 14 Sept 2015 | 4 | 1 |
| Unknown player | Thigh Problems | 8 Sept 2015 | 2 Nov 2015 | 55 | 12 |
| Unknown player | Cut | 28 Aug 2015 | 11 Sept 2015 | 14 | 1 |
| Unknown player | Ankle Injury | 21 Aug 2015 | 2 Nov 2015 | 73 | 14 |
| Unknown player | Knock | 6 Aug 2015 | 17 Aug 2015 | 11 | 2 |
| Unknown player | Groin Injury | 3 Aug 2015 | 10 Sept 2015 | 38 | 4 |
| Unknown player | Muscular Problems | 16 Apr 2015 | 5 May 2015 | 19 | 3 |
| Unknown player | Ankle Sprain | 6 Apr 2015 | 24 Apr 2015 | 18 | 3 |
 Unknown player | Muscular Problems | 2 Apr 2015 | 11 May 2015 | 39 | 6 |
 Unknown player | ILL | 22 Dec 2014 | 5 Jan 2015 | 14 | 3 |
 Edin Džeko | Calf Injury | 15 Dec 2014 | 5 Jan 2015 | 21 | 4 |
| Unknown player | Thigh Problems | 11 Dec 2014 | 25 Dec 2014 | 14 | 2 |
| Unknown player | Cruciate Ligament Injury | 8 Dec 2014 | 8 Jan 2015 | 31 | 7 |
| Edin Džeko | Calf Injury | 10 Nov 2014 | 4 Dec 2014 | 24 | 3 |
 Unknown player | Hamstring Strain | 10 Nov 2014 | 22 Dec 2014 | 42 | 8 |
 Unknown player | Calf Injury | 2 Nov 2014 | 5 Dec 2014 | 33 | 7 |
| Unknown player | Knee Injury | 30 Oct 2014 | 4 Dec 2014 | 35 | 7 |
| Unknown player | Groin Injury | 1 Sept 2014 | 2 Oct 2014 | 31 | 6 |
| Unknown player | Hamstring Injury | 1 Sept 2014 | 29 Sept 2014 | 28 | 5 |
 Unknown player | Metatarsal Fracture | 18 Jul 2014 | 18 Oct 2014 | 92 | 11 |
| Unknown player | Knee Problems | 13 Mar 2014 | 27 Mar 2014 | 14 | 3 |
| Unknown player | Hamstring Injury | 24 Feb 2014 | 20 Mar 2014 | 24 | 4 |
| Unknown player | Knee Injury | 6 Feb 2014 | 8 May 2014 | 91 | 18 |
| Unknown player | Muscle Injury | 30 Jan 2014 | 17 Feb 2014 | 18 | 3 |
| Unknown player | Hamstring Injury | 30 Jan 2014 | 27 Feb 2014 | 28 | 5 |
| Unknown player | Hamstring Injury | 16 Dec 2013 | 16 Jan 2014 | 31 | 9 |
| Unknown player | Calf Injury | 16 Dec 2013 | 13 Jan 2014 | 28 | 8 |
| Unknown player | Calf Problems | 28 Nov 2013 | 26 Dec 2013 | 28 | 7 |
| Unknown player | Knock | 9 Nov 2013 | 23 Nov 2013 | 14 | 1 |
| Unknown player | Calf Injury | 7 Nov 2013 | 5 Dec 2013 | 28 | 5 |
 Unknown player | Dead Leg | 1 Nov 2013 | 10 Nov 2013 | 9 | 2 |
| Unknown player | Calf Injury | 31 Oct 2013 | 9 Dec 2013 | 39 | 8 |
 Unknown player | Thigh Problems | 23 Sept 2013 | 24 Oct 2013 | 31 | 5 |
 Unknown player | Knee Surgery | 4 Jul 2013 | 1 Nov 2013 | 120 | 14 |
| Unknown player | Hamstring Injury | 4 Mar 2013 | 8 Apr 2013 | 35 | 4 |
| Unknown player | Knee Injury | 28 Feb 2013 | 28 Mar 2013 | 28 | 3 |
| Unknown player | Thigh Problems | 31 Dec 2012 | 17 Jan 2013 | 17 | 3 |
 Unknown player | ILL | 17 Dec 2012 | 3 Jan 2013 | 17 | 4 |
| Unknown player | Knee Injury | 15 Dec 2012 | 10 Jan 2013 | 26 | 6 |
 Unknown player | Hamstring Injury | 5 Nov 2012 | 19 Nov 2012 | 14 | 3 |
| Unknown player | Ankle Injury | 27 Oct 2012 | 2 Nov 2012 | 6 | 1 |
| Unknown player | Hamstring Injury | 18 Oct 2012 | 8 Nov 2012 | 21 | 5 |
| Unknown player | Hamstring Injury | 11 Oct 2012 | 17 Jan 2013 | 98 | 20 |
 Denis Suárez | Torn Lateral Ankle Ligament | 9 Oct 2012 | 17 Dec 2012 | 69 | 0 |
| Unknown player | Injury | 3 Oct 2012 | 1 Nov 2012 | 29 | 5 |
| Unknown player | Knee Injury | 20 Aug 2012 | 17 Sept 2012 | 28 | 3 |
| Unknown player | Laceration Wound | 22 Mar 2012 | 4 Apr 2012 | 13 | 2 |
| Unknown player | Ankle Injury | 12 Jan 2012 | 19 Jan 2012 | 7 | 1 |
| Unknown player | Ankle Injury | 5 Jan 2012 | 9 Jan 2012 | 4 | 0 |
| Unknown player | Adductor Pain | 2 Oct 2011 | 16 Oct 2011 | 14 | 1 |
 Unknown player | Knee Injury | 28 Mar 2011 | 27 Jun 2011 | 91 | 10 |
| Unknown player | Knee Problems | 3 Jan 2011 | 13 Jan 2011 | 10 | 2 |
| Unknown player | Knee Problems | 30 Dec 2010 | 10 Jan 2011 | 11 | 3 |
| Unknown player | Knee Surgery | 19 Aug 2010 | 25 Oct 2010 | 67 | 14 |
 Unknown player | Calf Problems | 18 Jan 2010 | 20 Feb 2010 | 33 | 8 |
 Unknown player | Virus | 4 Dec 2009 | 11 Dec 2009 | 7 | 1 |
