| Player | Reason | From | Until | Days | Games missed |
|---|---|---|---|---|---|
 Jan Paul van Hecke | Groin Injury | 23 Sept 2024 | 16 Oct 2024 | 23 | 2 |
 Yasin Ayari | ILL | 21 Sept 2024 | 23 Sept 2024 | 2 | 0 |
 Ferdi Kadıoğlu | Hamstring Injury | 30 Aug 2024 | 10 Sept 2024 | 11 | 1 |
 Matt O'Riley | Ankle Injury | 27 Aug 2024 | 8 Nov 2024 | 73 | 5 |
 Mats Wieffer | Injury | 24 Aug 2024 | 16 Sept 2024 | 23 | 3 |
 Brajan Gruda | Knock | 12 Aug 2024 | 14 Sept 2024 | 33 | 2 |
Unknown player | Muscle Injury | 10 Aug 2024 | 23 Aug 2024 | 13 | 2 |
Unknown player | Knock | 11 May 2024 | 21 May 2024 | 10 | 3 |
| Jan Paul van Hecke | Hamstring Injury | 26 Apr 2024 | 26 May 2024 | 30 | 5 |
 Pervis Estupiñán | Ankle Injury | 14 Apr 2024 | 31 Aug 2024 | 139 | 6 |
Unknown player | Muscle Injury | 8 Apr 2024 | 8 May 2024 | 30 | 4 |
 E. Ferguson | Cruciate Ligament Tear | 1 Apr 2024 | 25 Aug 2024 | 146 | 15 |
 Billy Gilmour | Knee Injury | 27 Mar 2024 | 26 Apr 2024 | 30 | 4 |
Unknown player | Muscle Injury | 27 Feb 2024 | 1 Mar 2024 | 3 | 1 |
 Kaoru Mitoma | Back Injury | 23 Feb 2024 | 30 Jun 2024 | 128 | 15 |
 João Pedro | Hamstring Injury | 7 Feb 2024 | 1 Apr 2024 | 54 | 8 |
 Jack Hinshelwood | Broken Foot | 4 Feb 2024 | 2 Aug 2024 | 180 | 21 |
Unknown player | Muscle Injury | 31 Jan 2024 | 12 Jun 2024 | 133 | 19 |
Unknown player | Hamstring Injury | 27 Dec 2023 | 20 Jan 2024 | 24 | 3 |
| Kaoru Mitoma | Ankle Injury | 22 Dec 2023 | 25 Jan 2024 | 34 | 4 |
Unknown player | Knee Injury | 17 Dec 2023 | 5 Feb 2024 | 50 | 9 |
Unknown player | Injury | 25 Nov 2023 | 7 Jan 2024 | 43 | 11 |
 Ansu Fati | Calf Injury | 25 Nov 2023 | 2 Feb 2024 | 69 | 14 |
Unknown player | Injury | 24 Nov 2023 | 1 Jan 2024 | 38 | 9 |
| Kaoru Mitoma | Injury | 15 Nov 2023 | 29 Nov 2023 | 14 | 1 |
| Pervis Estupiñán | Muscle Injury | 9 Nov 2023 | 27 Dec 2023 | 48 | 10 |
Unknown player | Knee Injury | 21 Oct 2023 | 23 Dec 2024 | 429 | 38 |
 Danny Welbeck | Hamstring Injury | 21 Oct 2023 | 16 Dec 2023 | 56 | 12 |
Unknown player | Muscle Injury | 6 Oct 2023 | 15 Nov 2023 | 40 | 7 |
| Pervis Estupiñán | Muscle Injury | 30 Sept 2023 | 8 Nov 2023 | 39 | 7 |
Unknown player | Muscle Injury | 20 Sept 2023 | 15 Oct 2023 | 25 | 6 |
| E. Ferguson | Knee Injury | 5 Sept 2023 | 23 Sept 2023 | 18 | 2 |
 Julio Enciso | Meniscus Tear | 22 Aug 2023 | 21 Feb 2024 | 183 | 32 |
Unknown player | Injury | 26 May 2023 | 16 Jul 2023 | 51 | 1 |
 Robert Sánchez | Knock | 13 May 2023 | 29 May 2023 | 16 | 4 |
Unknown player | Hamstring Injury | 12 May 2023 | 12 Jun 2023 | 31 | 5 |
Unknown player | Muscular Problems | 10 May 2023 | 22 May 2023 | 12 | 2 |
| E. Ferguson | Doubtful | 29 Apr 2023 | 29 Apr 2023 | 0 | 1 |
| E. Ferguson | Ankle Injury | 15 Apr 2023 | 5 May 2023 | 20 | 4 |
Unknown player | Metatarsal Fracture | 25 Mar 2023 | 1 Jun 2023 | 68 | 15 |
Unknown player | Knee Injury | 5 Mar 2023 | 30 Jun 2023 | 117 | 17 |
| Pervis Estupiñán | Muscular Problems | 19 Feb 2023 | 1 Mar 2023 | 10 | 0 |
 Levi Colwill | Doubtful | 4 Feb 2023 | 4 Feb 2023 | 0 | 1 |
Unknown player | Thigh Problems | 22 Jan 2023 | 14 Apr 2023 | 82 | 12 |
 Facundo Buonanotte | Cervical Spine Injury | 22 Jan 2023 | 1 Feb 2023 | 10 | 1 |
| Levi Colwill | Torn Muscle Bundle | 20 Jan 2023 | 25 Feb 2023 | 36 | 5 |
| Danny Welbeck | Injury | 23 Dec 2022 | 4 Jan 2023 | 12 | 2 |
Unknown player | Minor Knock | 20 Dec 2022 | 5 Jan 2023 | 16 | 4 |
Unknown player | Doubtful | 1 Oct 2022 | 23 Dec 2024 | 814 | — |
Unknown player | Doubtful | 1 Oct 2022 | 23 Dec 2024 | 814 | — |
Unknown player | Heart Problems | 30 Sept 2022 | 10 Oct 2022 | 10 | — |
Unknown player | Calf Injury | 26 Aug 2022 | 28 Sept 2022 | 33 | 3 |
Unknown player | Knee Injury | 14 Aug 2022 | 31 Aug 2022 | 17 | 3 |
Unknown player | Groin Injury | 30 Apr 2022 | 21 May 2022 | 21 | 3 |
Unknown player | Hamstring Injury | 26 Apr 2022 | 24 May 2022 | 28 | 4 |
Unknown player | Knee Injury | 21 Apr 2022 | 29 Apr 2022 | 8 | 1 |
Unknown player | Doubtful | 20 Apr 2022 | 6 Aug 2024 | 839 | 116 |
Unknown player | ILL | 19 Apr 2022 | 21 Apr 2022 | 2 | 0 |
Unknown player | ILL | 10 Apr 2022 | 19 Apr 2022 | 9 | 1 |
Unknown player | Thigh Problems | 3 Apr 2022 | 23 Apr 2022 | 20 | 3 |
Unknown player | Cruciate Ligament Tear | 2 Apr 2022 | 29 Oct 2023 | 575 | 50 |
 M. Caicedo | ILL | 1 Apr 2022 | 6 Apr 2022 | 5 | 1 |
Unknown player | Hamstring Injury | 12 Mar 2022 | 1 Apr 2022 | 20 | 2 |
Unknown player | Doubtful | 12 Mar 2022 | 6 Aug 2024 | 878 | — |
Unknown player | Groin Injury | 18 Feb 2022 | 8 Apr 2022 | 49 | 6 |
Unknown player | Ankle Injury | 14 Jan 2022 | 4 Feb 2022 | 21 | 3 |
Unknown player | Hamstring Injury | 14 Jan 2022 | 22 Jan 2022 | 8 | 2 |
Unknown player | Hamstring Injury | 8 Jan 2022 | 11 Mar 2022 | 62 | 10 |
Unknown player | Hamstring Injury | 26 Dec 2021 | 1 Jan 2022 | 6 | 2 |
Unknown player | COVID 19 | 16 Dec 2021 | 28 Dec 2021 | 12 | 1 |
Unknown player | Ankle Injury | 15 Dec 2021 | 28 Dec 2021 | 13 | 2 |
 Neal Maupay | COVID 19 | 14 Dec 2021 | 25 Dec 2021 | 11 | 1 |
 Pascal Groß | COVID 19 | 14 Dec 2021 | 25 Dec 2021 | 11 | 1 |
 Jason Steele | COVID 19 | 14 Dec 2021 | 28 Dec 2021 | 14 | 2 |
Unknown player | COVID 19 | 13 Dec 2021 | 3 Jan 2022 | 21 | 3 |
Unknown player | Hamstring Injury | 2 Dec 2021 | 10 Mar 2022 | 98 | 15 |
Unknown player | Leg Injury | 1 Dec 2021 | 14 Dec 2021 | 13 | 2 |
 Lewis Dunk | Knee Injury | 1 Dec 2021 | 22 Jan 2022 | 52 | 9 |
Unknown player | Calf Injury | 1 Dec 2021 | 25 Dec 2021 | 24 | 3 |
Unknown player | Doubtful | 30 Oct 2021 | 30 Oct 2021 | 0 | 1 |
 Dan Burn | Knee Injury | 27 Oct 2021 | 19 Nov 2021 | 23 | 3 |
| Danny Welbeck | Hamstring Injury | 27 Sept 2021 | 25 Dec 2021 | 89 | 12 |
Unknown player | Ankle Surgery | 27 Sept 2021 | 14 Dec 2021 | 78 | 11 |
Unknown player | Injury | 22 Sept 2021 | 14 Oct 2021 | 22 | 3 |
Unknown player | Knee Injury | 19 Sept 2021 | 14 Oct 2021 | 25 | 4 |
Unknown player | Hamstring Injury | 11 Sept 2021 | 18 Oct 2021 | 37 | 5 |
Unknown player | Doubtful | 28 Aug 2021 | 28 Aug 2021 | 0 | 1 |
Unknown player | Hamstring Injury | 28 Aug 2021 | 10 Sept 2021 | 13 | 1 |
| Neal Maupay | Shoulder Injury | 21 Aug 2021 | 27 Aug 2021 | 6 | 2 |
Unknown player | COVID 19 | 14 Aug 2021 | 27 Aug 2021 | 13 | 3 |
Unknown player | Ankle Injury | 1 Aug 2021 | 28 Jul 2022 | 361 | 48 |
| Dan Burn | Torn Knee Ligaments | 31 Jul 2021 | 18 Sept 2021 | 49 | 6 |
 Kjell Scherpen | Ankle Problems | 24 Jul 2021 | 10 Sept 2021 | 48 | 6 |
| Danny Welbeck | Hamstring Injury | 24 Jul 2021 | 27 Aug 2021 | 34 | 5 |
Unknown player | Bruise | 3 May 2021 | 1 Jun 2021 | 29 | 2 |
Unknown player | Injury | 24 Mar 2021 | 21 Apr 2021 | 28 | 2 |
Unknown player | Hamstring Injury | 6 Mar 2021 | 18 Sept 2021 | 196 | 19 |
Unknown player | Rest | 26 Feb 2021 | 28 Feb 2021 | 2 | 0 |
Unknown player | Ankle Injury | 7 Feb 2021 | 23 Feb 2021 | 16 | 2 |
Unknown player | Knock | 5 Feb 2021 | 1 Jul 2021 | 146 | 17 |
