| Player | Reason | From | Until | Days | Games missed |
|---|---|---|---|---|---|
 Alexander Sørloth | Muscle Injury | 12 Aug 2026 | 1 Sept 2026 | 20 | 4 |
 Johnny Cardoso | Ankle Surgery | 11 May 2026 | 10 Aug 2026 | 91 | 6 |
 Nahuel Molina | Muscle Injury | 10 May 2026 | 31 May 2026 | 21 | — |
| Johnny Cardoso | Ankle Sprain | 7 May 2026 | 10 May 2026 | 3 | 1 |
 Julián Alvarez | Ankle Sprain | 6 May 2026 | 31 May 2026 | 25 | 4 |
| Julián Alvarez | Ankle Problems | 30 Apr 2026 | 4 May 2026 | 4 | 1 |
 Nico González | Muscle Injury | 28 Apr 2026 | 5 Jun 2026 | 38 | 5 |
 Pablo Barrios | Muscle Injury | 25 Apr 2026 | 1 Jun 2026 | 37 | 7 |
 Dávid Hancko | Ankle Injury | 8 Apr 2026 | 28 Apr 2026 | 20 | 6 |
 José María Giménez | Muscle Injury | 7 Apr 2026 | 3 May 2026 | 26 | 8 |
 Marc Pubill | Bruised Ribs | 19 Mar 2026 | 6 Apr 2026 | 18 | 2 |
| Pablo Barrios | Muscle Injury | 10 Mar 2026 | 17 Apr 2026 | 38 | 6 |
 Rodrigo Mendoza | Ankle Sprain | 7 Mar 2026 | 5 Apr 2026 | 29 | 6 |
| Nico González | Muscle Injury | 16 Feb 2026 | 2 Mar 2026 | 14 | 4 |
 Jan Oblak | Muscle Injury | 12 Feb 2026 | 13 Apr 2026 | 60 | 15 |
| Marc Pubill | Stomach Flu | 8 Feb 2026 | 9 Feb 2026 | 1 | 1 |
| Pablo Barrios | Muscle Injury | 5 Feb 2026 | 5 Mar 2026 | 28 | 9 |
 Giuliano Simeone | Fever | 29 Jan 2026 | 3 Feb 2026 | 5 | 1 |
 Unknown player | Hamstring Injury | 23 Jan 2026 | 2 Feb 2026 | 10 | 3 |
| Pablo Barrios | Calf Problems | 4 Jan 2026 | 12 Jan 2026 | 8 | 2 |
| Nico González | Muscle Injury | 21 Dec 2025 | 19 Jan 2026 | 29 | 6 |
 Unknown player | Inner Ligament Injury | 7 Dec 2025 | 23 Jan 2026 | 47 | 9 |
 Álex Baena | Hamstring Injury | 3 Dec 2025 | 20 Dec 2025 | 17 | 2 |
| Johnny Cardoso | Knee Bruise | 2 Dec 2025 | 10 Dec 2025 | 8 | 2 |
| José María Giménez | Hamstring Injury | 2 Dec 2025 | 1 Jan 2026 | 30 | 6 |
 Marcos Llorente | Hamstring Injury | 22 Nov 2025 | 21 Dec 2025 | 29 | 8 |
 Robin Le Normand | Knee Injury | 4 Nov 2025 | 5 Dec 2025 | 31 | 6 |
 Unknown player | Cruciate Ligament Tear | 10 Oct 2025 | 1 Jul 2026 | 264 | 33 |
| Johnny Cardoso | Ankle Injury | 16 Sept 2025 | 30 Oct 2025 | 44 | 10 |
| Julián Alvarez | Inner Ligament Injury | 14 Sept 2025 | 20 Sept 2025 | 6 | 1 |
 Unknown player | Muscle Injury | 11 Sept 2025 | 11 Oct 2025 | 30 | 7 |
| Álex Baena | Appendicitis | 3 Sept 2025 | 22 Sept 2025 | 19 | 2 |
| Álex Baena | Muscle Injury | 18 Aug 2025 | 2 Sept 2025 | 15 | 2 |
| José María Giménez | Hamstring Injury | 21 Jun 2025 | 13 Oct 2025 | 114 | 14 |
 Unknown player | Muscle Tear | 4 Apr 2025 | 16 Apr 2025 | 12 | 2 |
 Koke | Muscle Injury | 16 Feb 2025 | 1 Apr 2025 | 44 | 8 |
 Javi Galán | Injury | 29 Jan 2025 | — | — | 100 |
| Alexander Sørloth | Muscle Injury | 15 Jan 2025 | 23 Jan 2025 | 8 | 5 |
| José María Giménez | Muscle Injury | 21 Dec 2024 | 20 Jan 2025 | 30 | 5 |
| Nahuel Molina | Muscle Injury | 18 Nov 2024 | 6 Dec 2024 | 18 | 3 |
 Thomas Lemar | Muscle Injury | 28 Oct 2024 | 9 Dec 2024 | 42 | 9 |
| Unknown player | Sprain | 20 Oct 2024 | 1 Nov 2024 | 12 | 3 |
| Pablo Barrios | Muscle Injury | 20 Oct 2024 | 2 Nov 2024 | 13 | 4 |
| Marcos Llorente | Hamstring Injury | 3 Oct 2024 | 3 Nov 2024 | 31 | 4 |
| Robin Le Normand | Head Injury | 1 Oct 2024 | 30 Nov 2024 | 60 | 0 |
 Unknown player | Muscle Injury | 22 Sept 2024 | 6 Nov 2024 | 45 | 10 |
| Pablo Barrios | Muscle Injury | 8 Sept 2024 | 5 Oct 2024 | 27 | 5 |
| Thomas Lemar | Muscle Injury | 17 Aug 2024 | 27 Sept 2024 | 41 | 7 |
| Pablo Barrios | Muscle Injury | 15 May 2024 | 24 Jun 2024 | 40 | 3 |
| Nahuel Molina | Muscle Injury | 5 May 2024 | 11 Jun 2024 | 37 | 3 |
 Álvaro Morata | Toothache | 19 Apr 2024 | 24 Apr 2024 | 5 | 1 |
 Unknown player | Muscle Injury | 9 Apr 2024 | 11 May 2024 | 32 | 6 |
| Unknown player | Muscle Injury | 8 Apr 2024 | 6 May 2024 | 28 | 6 |
 Mario Hermoso | Muscle Injury | 16 Mar 2024 | 11 Apr 2024 | 26 | 4 |
| Pablo Barrios | Flu | 8 Mar 2024 | 11 Mar 2024 | 3 | 1 |
| Unknown player | Ankle Injury | 21 Feb 2024 | 12 Mar 2024 | 20 | 4 |
| José María Giménez | Muscle Injury | 21 Feb 2024 | 29 Mar 2024 | 37 | 6 |
| Álvaro Morata | Inner Ligament Stretch Of The Knee | 11 Feb 2024 | 20 Feb 2024 | 9 | 9 |
| Álvaro Morata | Thigh Problems | 29 Jan 2024 | 1 Feb 2024 | 3 | 1 |
| José María Giménez | Hamstring Injury | 28 Jan 2024 | 17 Feb 2024 | 20 | 5 |
| Unknown player | Meniscus Tear | 19 Jan 2024 | 10 Mar 2024 | 51 | 13 |
| Unknown player | Muscle Injury | 8 Dec 2023 | 8 May 2024 | 152 | 20 |
| Pablo Barrios | Meniscus Damage | 29 Nov 2023 | 19 Jan 2024 | 51 | 12 |
 Unknown player | Knee Injury | 22 Oct 2023 | 5 Nov 2023 | 14 | 3 |
 Unknown player | Internal Ligament Tear | 5 Oct 2023 | 18 Oct 2023 | 13 | 1 |
| José María Giménez | Muscle Injury | 3 Oct 2023 | 26 Oct 2023 | 23 | 3 |
| Unknown player | Muscle Injury | 26 Sept 2023 | 24 Nov 2023 | 59 | 10 |
| Unknown player | Knee Problems | 26 Sept 2023 | 30 Sept 2023 | 4 | 1 |
| Pablo Barrios | Muscle Injury | 19 Sept 2023 | 20 Oct 2023 | 31 | 7 |
| Thomas Lemar | Achilles Tendon Rupture | 17 Sept 2023 | 17 May 2024 | 243 | 37 |
| Unknown player | Muscle Injury | 15 Sept 2023 | 20 Sept 2023 | 5 | 1 |
| Unknown player | Hamstring Injury | 12 Sept 2023 | 29 Sept 2023 | 17 | 3 |
 Unknown player | Groin Problems | 12 Sept 2023 | 20 Oct 2023 | 38 | 8 |
| Unknown player | Doubtful | 20 Aug 2023 | 20 Aug 2023 | 0 | 1 |
| Koke | Muscle Injury | 15 Aug 2023 | 22 Sept 2023 | 38 | 5 |
| Unknown player | Ankle Sprain | 15 Aug 2023 | 25 Aug 2023 | 10 | 1 |
| Nahuel Molina | Doubtful | 14 Aug 2023 | 14 Aug 2023 | 0 | — |
| Nahuel Molina | Muscle Injury | 24 Jul 2023 | 18 Aug 2023 | 25 | 5 |
| José María Giménez | Knee Injury | 31 May 2023 | 14 Sept 2023 | 106 | 9 |
| Álvaro Morata | Neck Injury | 22 May 2023 | 25 May 2023 | 3 | 1 |
| Unknown player | Calf Injury | 2 May 2023 | 30 Jul 2023 | 89 | 6 |
| Jan Oblak | Back Injury | 25 Apr 2023 | 26 Jul 2023 | 92 | 8 |
 Unknown player | Broken Toe | 3 Apr 2023 | 25 May 2023 | 52 | 10 |
| Marcos Llorente | Muscle Injury | 3 Apr 2023 | 30 Jul 2023 | 118 | 13 |
| Unknown player | Muscle Injury | 1 Apr 2023 | 25 Apr 2023 | 24 | 5 |
 Reinildo Mandava | Cruciate Ligament Tear | 25 Feb 2023 | 25 Nov 2023 | 273 | 25 |
| Unknown player | Muscle Tear | 20 Feb 2023 | 10 Mar 2023 | 18 | 2 |
 Unknown player | Hamstring Injury | 20 Feb 2023 | 13 Mar 2023 | 21 | 2 |
 Unknown player | Muscle Injury | 15 Jan 2023 | 20 Jan 2023 | 5 | 2 |
| José María Giménez | Injury | 13 Jan 2023 | 28 Jan 2023 | 15 | 4 |
 Geoffrey Kondogbia | Muscle Strain | 7 Nov 2022 | 1 Dec 2022 | 24 | 2 |
| Koke | Muscle Injury | 18 Oct 2022 | 8 Nov 2022 | 21 | 5 |
| José María Giménez | Back Problems | 9 Sept 2022 | 28 Sept 2022 | 19 | 3 |
 Matheus Cunha | Muscle Injury | 2 Sept 2022 | 9 Sept 2022 | 7 | 2 |
| Thomas Lemar | Muscle Injury | 2 Sept 2022 | 5 Sept 2022 | 3 | 1 |
| Unknown player | Muscle Injury | 22 Aug 2022 | 30 Sept 2022 | 39 | 6 |
| José María Giménez | Tonsillitis | 7 Aug 2022 | 19 Aug 2022 | 12 | 2 |
| Mario Hermoso | ILL | 6 May 2022 | 10 May 2022 | 4 | 1 |
| Thomas Lemar | Muscle Injury | 18 Apr 2022 | 20 May 2022 | 32 | 5 |
 Unknown player | Muscle Injury | 18 Apr 2022 | 1 Jul 2022 | 74 | 6 |
