| Player | Reason | From | Until | Days | Games missed |
|---|---|---|---|---|---|
 Pau Torres | Injury | 18 Dec 2023 | 23 Dec 2023 | 5 | 0 |
 Youri Tielemans | Calf Injury | 13 Dec 2023 | 12 Jan 2024 | 30 | 6 |
 Unknown player | Injury | 25 Nov 2023 | 13 Jan 2024 | 49 | 11 |
 Unknown player | Infection | 28 Oct 2023 | 6 Nov 2023 | 9 | 1 |
| Unknown player | Infection | 21 Oct 2023 | 23 Oct 2023 | 2 | 0 |
 Jacob Ramsey | Foot Injury | 4 Oct 2023 | 24 Nov 2023 | 51 | 8 |
 Unknown player | Hamstring Injury | 27 Sept 2023 | 7 Oct 2023 | 10 | 3 |
| Unknown player | Injury | 30 Aug 2023 | 25 Sept 2023 | 26 | 4 |
 Unknown player | Hamstring Injury | 20 Aug 2023 | 25 Sept 2023 | 36 | 7 |
 Tyrone Mings | Cruciate Ligament Tear | 12 Aug 2023 | 30 Oct 2024 | 445 | 56 |
| Unknown player | Injury | 11 Aug 2023 | 13 Aug 2023 | 2 | 1 |
 Emiliano Buendía | Cruciate Ligament Tear | 9 Aug 2023 | 1 Jul 2024 | 327 | 34 |
 Nicolò Zaniolo | Groin Problems | 1 Aug 2023 | 22 Aug 2023 | 21 | 5 |
 Unknown player | Injury | 1 Aug 2023 | 1 Sept 2023 | 31 | 6 |
| Jacob Ramsey | Metatarsal Fracture | 2 Jul 2023 | 20 Sept 2023 | 80 | 13 |
 Unknown player | Injury | 26 May 2023 | 8 Jul 2023 | 43 | 1 |
 Unknown player | Hamstring Injury | 20 May 2023 | 15 Sept 2023 | 118 | 14 |
 Matty Cash | Fitness | 4 May 2023 | 8 May 2023 | 4 | 1 |
| Unknown player | Hamstring Injury | 8 Apr 2023 | 1 May 2023 | 23 | 4 |
 Boubacar Kamara | Ankle Injury | 4 Apr 2023 | 30 Apr 2023 | 26 | 5 |
| Matty Cash | Calf Injury | 29 Mar 2023 | 3 May 2023 | 35 | 4 |
| Boubacar Kamara | Ankle Injury | 12 Mar 2023 | 18 Mar 2023 | 6 | 1 |
| Unknown player | Hand Injury | 1 Mar 2023 | 23 Mar 2023 | 22 | 3 |
 Unknown player | Doubtful | 21 Jan 2023 | 21 Jan 2023 | 0 | 1 |
 Lucas Digne | Shoulder Injury | 14 Jan 2023 | 3 Feb 2023 | 20 | 1 |
 John McGinn | Hamstring Strain | 1 Jan 2023 | 4 Feb 2023 | 34 | 5 |
| Unknown player | Knee Injury | 28 Dec 2022 | 15 Feb 2023 | 49 | 7 |
| Jacob Ramsey | Hamstring Injury | 23 Nov 2022 | 8 Jan 2023 | 46 | 7 |
| Unknown player | Hamstring Injury | 5 Nov 2022 | 25 Dec 2022 | 50 | 7 |
| Unknown player | Muscle Injury | 8 Oct 2022 | 14 Oct 2022 | 6 | 1 |
 Unknown player | Hamstring Injury | 2 Oct 2022 | 31 Oct 2022 | 29 | 8 |
| Lucas Digne | Ankle Injury | 17 Sept 2022 | 27 Oct 2022 | 40 | 5 |
| Boubacar Kamara | Knee Injury | 15 Sept 2022 | 31 Oct 2022 | 46 | 7 |
| Matty Cash | Tendon Rupture | 3 Sept 2022 | 28 Sept 2022 | 25 | 2 |
 Diego Carlos | Achilles Tendon Rupture | 11 Aug 2022 | 12 Mar 2023 | 213 | 31 |
 Emiliano Martínez | Knee Problems | 20 May 2022 | 29 May 2022 | 9 | 1 |
 Ezri Konsa | Knee Injury | 15 May 2022 | 10 Jul 2022 | 56 | 3 |
| Unknown player | Cruciate Ligament Injury | 1 May 2022 | 31 May 2022 | 30 | 5 |
 Morgan Sanson | Knock | 10 Apr 2022 | 8 May 2022 | 28 | 2 |
| Lucas Digne | Shoulder Injury | 9 Apr 2022 | 25 Apr 2022 | 16 | 2 |
| Lucas Digne | Hamstring Injury | 14 Mar 2022 | 21 Mar 2022 | 7 | 1 |
 Unknown player | Knee Injury | 7 Mar 2022 | 30 Jun 2022 | 115 | 12 |
| Unknown player | Doubtful | 5 Mar 2022 | 6 Aug 2024 | 885 | — |
| Unknown player | COVID 19 | 10 Jan 2022 | 16 Jan 2022 | 6 | 1 |
| Morgan Sanson | COVID 19 | 12 Dec 2021 | 25 Dec 2021 | 13 | 1 |
 Unknown player | Knee Injury | 11 Dec 2021 | 31 Mar 2022 | 110 | 15 |
| Unknown player | Thigh Problems | 5 Dec 2021 | 10 Feb 2022 | 67 | 8 |
 Jaden Philogene | Doubtful | 5 Nov 2021 | 5 Nov 2021 | 0 | 1 |
| Morgan Sanson | ILL | 30 Oct 2021 | 6 Nov 2021 | 7 | 1 |
 Douglas Luiz | Hamstring Injury | 25 Oct 2021 | 25 Nov 2021 | 31 | 3 |
| Unknown player | Strain In The Thigh And Gluteal Muscles | 20 Oct 2021 | 25 Dec 2021 | 66 | 9 |
| Morgan Sanson | Hamstring Injury | 23 Sept 2021 | 16 Oct 2021 | 23 | 2 |
| Unknown player | Thigh Problems | 19 Sept 2021 | 21 Oct 2021 | 32 | 4 |
| Unknown player | Hamstring Injury | 20 Aug 2021 | 9 Sept 2021 | 20 | 3 |
 Keinan Davis | Knee Injury | 14 Aug 2021 | 25 Sept 2021 | 42 | 7 |
 Unknown player | Knee Surgery | 10 Apr 2021 | 4 Dec 2021 | 238 | 29 |
| Morgan Sanson | Knee Problems | 9 Apr 2021 | 29 Aug 2021 | 142 | 16 |
 Jack Grealish | Shin Injury | 20 Feb 2021 | 10 May 2021 | 79 | 11 |
| Matty Cash | Hamstring Injury | 18 Feb 2021 | 7 Mar 2021 | 17 | 3 |
 Ross Barkley | Doubtful | 20 Jan 2021 | 20 Jan 2021 | 0 | 1 |
| Unknown player | Ankle Injury | 3 Jan 2021 | 5 Apr 2021 | 92 | 14 |
 Unknown player | Knee Injury | 2 Jan 2021 | 24 Apr 2021 | 112 | 17 |
| Keinan Davis | Doubtful | 17 Dec 2020 | 17 Dec 2020 | 0 | 1 |
| Ezri Konsa | Bruise | 13 Dec 2020 | 25 Dec 2020 | 12 | 2 |
| Unknown player | Doubtful | 12 Dec 2020 | 12 Dec 2020 | 0 | 1 |
 Unknown player | Doubtful | 12 Dec 2020 | 12 Dec 2020 | 0 | 1 |
| Unknown player | Head Injury | 1 Dec 2020 | 21 Jan 2021 | 51 | 7 |
| Ross Barkley | Hamstring Injury | 21 Nov 2020 | 19 Jan 2021 | 59 | 9 |
 Tom Heaton | Knock | 10 Nov 2020 | 12 Dec 2020 | 32 | 2 |
| Keinan Davis | Ankle Injury | 9 Nov 2020 | 16 Dec 2020 | 37 | 3 |
| Unknown player | Bruised Ribs | 2 Nov 2020 | 20 Nov 2020 | 18 | 1 |
 Unknown player | Hamstring Injury | 2 Nov 2020 | 16 Dec 2020 | 44 | 4 |
| Unknown player | Groin Injury | 2 Oct 2020 | 11 Dec 2020 | 70 | 7 |
| Unknown player | Chest Injury | 2 Oct 2020 | 11 Dec 2020 | 70 | 7 |
 Ørjan Nyland | Back Injury | 2 Oct 2020 | 31 Jan 2021 | 121 | 17 |
 Unknown player | Hamstring Injury | 13 Jul 2020 | 25 Jul 2020 | 12 | 2 |
| Unknown player | Bruised Ribs | 10 Jul 2020 | 20 Jul 2020 | 10 | 2 |
 Matt Targett | Muscle Strain | 28 Jun 2020 | 11 Jul 2020 | 13 | 2 |
| Unknown player | Calf Injury | 18 Jun 2020 | 18 Oct 2020 | 122 | 17 |
 Unknown player | Injury | 11 Jun 2020 | 26 Jun 2020 | 15 | 3 |
| Unknown player | Knee Injury | 19 May 2020 | 4 Jul 2020 | 46 | 4 |
| Keinan Davis | Muscle Strain | 5 Feb 2020 | 29 Feb 2020 | 24 | 2 |
| Unknown player | Calf Injury | 23 Jan 2020 | 15 Feb 2020 | 23 | 2 |
| Tom Heaton | Cruciate Ligament Injury | 1 Jan 2020 | 7 Nov 2020 | 311 | 33 |
| Unknown player | Cruciate Ligament Tear | 1 Jan 2020 | 1 Jan 2021 | 366 | 41 |
| Matt Targett | Hamstring Injury | 31 Dec 2019 | 17 Jan 2020 | 17 | 4 |
| John McGinn | Ankle Injury | 21 Dec 2019 | 5 Jun 2020 | 167 | 15 |
| Tyrone Mings | Muscle Strain | 9 Dec 2019 | 31 Dec 2019 | 22 | 5 |
 Unknown player | Knee Injury | 2 Dec 2019 | 7 Dec 2019 | 5 | 1 |
| Tom Heaton | Calf Injury | 10 Nov 2019 | 24 Nov 2019 | 14 | 1 |
| Unknown player | Groin Injury | 3 Nov 2019 | 30 Nov 2019 | 27 | 2 |
| Keinan Davis | Muscle Strain | 1 Nov 2019 | 31 Jan 2020 | 91 | 18 |
| Jack Grealish | Calf Injury | 27 Oct 2019 | 24 Nov 2019 | 28 | 3 |
 Unknown player | Ankle Injury | 23 Sept 2019 | 4 Oct 2019 | 11 | 2 |
| Matt Targett | Hamstring Injury | 29 Aug 2019 | 24 Sept 2019 | 26 | 3 |
| Unknown player | Ankle Injury | 11 Aug 2019 | 22 Aug 2019 | 11 | 1 |
 Unknown player | Hamstring Injury | 8 Aug 2019 | 9 Nov 2019 | 93 | 14 |
| Jack Grealish | Fever | 12 Apr 2019 | 16 Apr 2019 | 4 | 1 |
| Unknown player | Hip Flexor Problems | 6 Apr 2019 | 29 Apr 2019 | 23 | 3 |
 Unknown player | Cartilage Damage | 24 Mar 2019 | 30 Apr 2019 | 37 | 7 |
