Competition
| Player | Team | Season | Reason | From | Until | Days | Games missed |
|---|---|---|---|---|---|---|---|
 Iván Balliu |  Rayo Vallecano | 2026/2027 | Ankle Injury | 11 Sept 2026 | Current | 15 | 1 |
 Gorka Guruzeta |  Athletic Club | 2026/2027 | Hamstring Injury | 9 Sept 2026 | Current | 31 | 1 |
 Mouctar Diakhaby |  Valencia | 2026/2027 | Hamstring Injury | 9 Sept 2026 | Current | 30 | 1 |
 Moi Gómez |  Osasuna | 2026/2027 | Muscle Injury | 8 Sept 2026 | Current | 22 | 1 |
 Simon Eriksson |  Racing Santander | 2026/2027 | Tendonitis | 8 Sept 2026 | Current | — | 1 |
 Kiko Femenía |  Getafe | 2026/2027 | Hamstring Injury | 7 Sept 2026 | Current | 54 | 2 |
 Julen Lobete |  Málaga | 2026/2027 | Cruciate Ligament Tear | 4 Sept 2026 | Current | 299 | 2 |
 Mikel Rodriguez |  Deportivo Alavés | 2026/2027 | Cruciate Ligament Injury | 4 Sept 2026 | Current | 212 | 2 |
 Rubén Vargas |  Sevilla | 2026/2027 | Knee Problems | 3 Sept 2026 | Current | — | 2 |
 Umar Sadiq | Valencia | 2026/2027 | Hamstring Injury | 1 Sept 2026 | Current | 62 | 2 |
 Andrés Martín | Racing Santander | 2026/2027 | Knee Injury | 29 Aug 2026 | Current | — | 2 |
 Augusto Batalla | Rayo Vallecano | 2026/2027 | Broken Leg | 21 Aug 2026 | Current | 93 | 3 |
| Rubén Vargas | Sevilla | 2026/2027 | Knee Problems | 21 Aug 2026 | Current | — | 4 |
 Noé Carrillo |  Deportivo A Coruña | 2026/2027 | Ankle Injury | 12 Aug 2026 | Current | — | 6 |
 Roony Bardghji |  FC Barcelona | 2026/2027 | Cruciate Ligament Tear | 10 Aug 2026 | Current | 273 | 8 |
 Kike García |  Espanyol | 2026/2027 | Muscle Injury | 4 Aug 2026 | Current | — | 6 |
 Thibaut Courtois |  Real Madrid | 2026/2027 | Hamstring Muscle Injury | 10 Jul 2026 | Current | — | 11 |
 Frenkie de Jong | FC Barcelona | 2026/2027 | Knee Medial Ligament Tear | 30 Jun 2026 | Current | 153 | 11 |
 Diego López | Valencia | 2026/2027 | Cruciate Ligament Tear | 23 May 2026 | Current | 282 | 12 |
 Ferland Mendy | Real Madrid | 2026/2027 | Tendon Rupture | 3 May 2026 | Current | 362 | 16 |
 Rodrygo | Real Madrid | 2026/2027 | Cruciate Ligament Injury | 3 Mar 2026 | Current | 211 | 27 |
 Álvaro Odriozola |  Real Sociedad | 2026/2027 | Cruciate Ligament Tear | 22 Feb 2026 | Current | 281 | 28 |
 Raúl de Tomás | Rayo Vallecano | 2026/2027 | Injury | 7 Jan 2026 | Current | — | 37 |
 Sergi Cardona |  Villarreal | 2026/2027 | Muscle Injury | 17 Dec 2025 | Current | — | 39 |
 Javi Guerra | Valencia | 2026/2027 | Flu | 11 Dec 2025 | Current | — | 37 |
 Iñigo Ruiz de Galarreta | Athletic Club | 2026/2027 | Injury | 26 Jan 2025 | Current | — | 94 |
 Arsen Zakharyan | Real Sociedad | 2026/2027 | Injury | 26 Jan 2025 | Current | — | 86 |
