| Player | Reason | From | Until | Days | Games missed |
|---|---|---|---|---|---|
 Hans Nicolussi Caviglia | Cruciate Ligament Tear | 15 Dec 2020 | 6 Jun 2021 | 173 | 28 |
 Unknown player | Bruise | 3 Dec 2020 | 17 Dec 2020 | 14 | 2 |
 Unknown player | Injury | 2 Dec 2020 | 13 Jan 2021 | 42 | 8 |
 Unknown player | Muscular Problems | 1 Dec 2020 | 1 Jan 2021 | 31 | 5 |
 Unknown player | Muscle Fatigue | 28 Nov 2020 | 7 Dec 2020 | 9 | 1 |
 Simon Sohm | Ankle Injury | 28 Nov 2020 | 8 Dec 2020 | 10 | 2 |
 Unknown player | Hamstring Injury | 22 Nov 2020 | 7 Dec 2020 | 15 | 3 |
 Unknown player | Injury | 21 Nov 2020 | 28 Nov 2020 | 7 | 2 |
 Lautaro Valenti | Adductor Pain | 17 Nov 2020 | 29 Nov 2020 | 12 | 2 |
| Hans Nicolussi Caviglia | Tonsillitis | 30 Oct 2020 | 5 Nov 2020 | 6 | 1 |
 Unknown player | Hamstring Muscle Injury | 29 Oct 2020 | 19 Nov 2020 | 21 | 2 |
 Unknown player | Muscular Problems | 27 Oct 2020 | 31 Dec 2020 | 65 | 11 |
| Unknown player | Injury | 24 Oct 2020 | 7 Nov 2020 | 14 | 3 |
 Unknown player | COVID 19 | 17 Oct 2020 | 2 Nov 2020 | 16 | 4 |
 Unknown player | Injury | 17 Oct 2020 | 4 Nov 2020 | 18 | 4 |
| Lautaro Valenti | Injury | 17 Oct 2020 | 27 Oct 2020 | 10 | 2 |
 Unknown player | COVID 19 | 16 Oct 2020 | 27 Oct 2020 | 11 | 2 |
 Unknown player | COVID 19 | 16 Oct 2020 | 27 Oct 2020 | 11 | 2 |
 Unknown player | Muscular Problems | 12 Oct 2020 | 27 Oct 2020 | 15 | 2 |
| Unknown player | Pubalgia | 5 Oct 2020 | 30 Oct 2020 | 25 | 3 |
| Unknown player | Adductor Pain | 5 Oct 2020 | 22 Oct 2020 | 17 | 1 |
 Unknown player | Injury | 5 Oct 2020 | 3 Nov 2020 | 29 | 4 |
| Unknown player | Muscular Problems | 20 Sept 2020 | 2 Oct 2020 | 12 | 2 |
 Unknown player | Heel Spur | 16 Sept 2020 | 2 Oct 2020 | 16 | 2 |
 Unknown player | Muscle Fatigue | 16 Sept 2020 | 26 Sept 2020 | 10 | 1 |
 Unknown player | Muscle Fatigue | 16 Sept 2020 | 26 Sept 2020 | 10 | 1 |
 Unknown player | Injury | 1 Sept 2020 | 2 Nov 2020 | 62 | 11 |
| Unknown player | Muscular Problems | 27 Jul 2020 | 30 Jul 2020 | 3 | 1 |
 Unknown player | Calf Muscle Tear | 23 Jul 2020 | 15 Aug 2020 | 23 | 3 |
| Unknown player | Left Hip Flexor Problems | 20 Jul 2020 | 24 Jul 2020 | 4 | 1 |
| Unknown player | Bone Bruise | 16 Jul 2020 | 21 Jul 2020 | 5 | 1 |
| Unknown player | Hamstring Muscle Injury | 16 Jul 2020 | 30 Jul 2020 | 14 | 4 |
| Unknown player | Calf Muscle Tear | 13 Jul 2020 | 5 Aug 2020 | 23 | 6 |
| Unknown player | Muscle Fatigue | 13 Jul 2020 | 23 Jul 2020 | 10 | 2 |
| Unknown player | Muscular Problems | 9 Jul 2020 | 16 Jul 2020 | 7 | 1 |
 Andrea Adorante | Doubtful | 28 Jun 2020 | 28 Jun 2020 | 0 | 1 |
 Unknown player | Achilles Tendon Rupture | 23 Jun 2020 | 2 Feb 2021 | 224 | — |
 Unknown player | Injury | 15 Jun 2020 | 25 Jun 2020 | 10 | 2 |
| Unknown player | Injury | 15 Jun 2020 | 29 Jun 2020 | 14 | 2 |
| Unknown player | Injury | 15 Jun 2020 | 22 Jun 2020 | 7 | 1 |
| Unknown player | Lumbago | 5 Mar 2020 | 12 Mar 2020 | 7 | 1 |
| Unknown player | Hamstring Strain | 28 Feb 2020 | 28 Mar 2020 | 29 | 1 |
| Unknown player | Calf Muscle Tear | 22 Feb 2020 | 22 Mar 2020 | 29 | 1 |
| Unknown player | Hamstring Strain | 13 Feb 2020 | 2 Mar 2020 | 18 | 1 |
 Dejan Kulusevski | Adductor Pain | 11 Feb 2020 | 20 Feb 2020 | 9 | 1 |
 Unknown player | Hamstring Injury | 10 Feb 2020 | 31 Mar 2020 | 50 | 2 |
| Unknown player | Hamstring Strain | 30 Jan 2020 | 15 Mar 2020 | 45 | 4 |
| Dejan Kulusevski | Left Hip Flexor Problems | 27 Jan 2020 | 7 Feb 2020 | 11 | 1 |
 Unknown player | Adductor Injury | 26 Jan 2020 | 30 Apr 2020 | 95 | 5 |
| Andrea Adorante | Knee Surgery | 24 Jan 2020 | 1 Apr 2020 | 68 | 5 |
| Unknown player | Thigh Problems | 21 Jan 2020 | 28 Jan 2020 | 7 | 1 |
| Unknown player | Hamstring Injury | 20 Jan 2020 | 11 Jul 2020 | 173 | 11 |
 Unknown player | Head Injury | 18 Jan 2020 | 31 Jan 2020 | 13 | — |
| Unknown player | Thigh Problems | 16 Jan 2020 | 28 Jan 2020 | 12 | 3 |
| Unknown player | Lumbago | 15 Jan 2020 | 20 Jan 2020 | 5 | 1 |
| Unknown player | Biceps Femoris Muscle Injury | 23 Dec 2019 | 11 Jan 2020 | 19 | 1 |
| Unknown player | Hamstring Strain | 12 Dec 2019 | 6 Jan 2020 | 25 | 2 |
| Unknown player | Calf Injury | 10 Dec 2019 | 30 Dec 2019 | 20 | 2 |
| Unknown player | Calf Muscle Tear | 9 Dec 2019 | 23 Dec 2019 | 14 | 1 |
| Unknown player | Calf Problems | 4 Dec 2019 | 7 Dec 2019 | 3 | 1 |
| Unknown player | Muscle Fatigue | 2 Dec 2019 | 6 Dec 2019 | 4 | 0 |
| Unknown player | Thigh Problems | 2 Dec 2019 | 9 Dec 2019 | 7 | 1 |
| Unknown player | Calf Problems | 2 Dec 2019 | 7 Dec 2019 | 5 | 1 |
| Unknown player | Muscle Bruise | 2 Dec 2019 | 6 Dec 2019 | 4 | 0 |
| Unknown player | Hamstring Muscle Injury | 18 Nov 2019 | 2 Dec 2019 | 14 | 1 |
| Unknown player | Thigh Muscle Strain | 11 Nov 2019 | 26 Nov 2019 | 15 | 1 |
 Unknown player | Outer Ligament Tear | 4 Nov 2019 | 4 Feb 2020 | 92 | 13 |
| Unknown player | Hamstring Muscle Injury | 27 Oct 2019 | 2 Nov 2019 | 6 | 1 |
| Unknown player | Knee Surgery | 23 Oct 2019 | 22 Nov 2019 | 30 | 4 |
| Unknown player | Hamstring Muscle Injury | 21 Oct 2019 | 4 Nov 2019 | 14 | 2 |
| Unknown player | Ankle Sprain | 21 Oct 2019 | 3 Jan 2020 | 74 | 10 |
| Unknown player | Hamstring Muscle Injury | 19 Oct 2019 | 9 Nov 2019 | 21 | 4 |
| Unknown player | Shoulder Injury | 1 Oct 2019 | 9 Nov 2019 | 39 | 5 |
 Unknown player | Hamstring Strain | 27 Sept 2019 | 15 Oct 2019 | 18 | 2 |
| Unknown player | Calf Problems | 12 Sept 2019 | 30 Sept 2019 | 18 | 3 |
| Unknown player | Stress Reaction Of The Bone | 11 Sept 2019 | 20 Sept 2019 | 9 | 1 |
| Unknown player | Knee Problems | 11 Sept 2019 | 1 Oct 2019 | 20 | 3 |
 Unknown player | Fitness | 16 Aug 2019 | 26 Aug 2019 | 10 | 2 |
| Unknown player | Injury | 24 May 2019 | 28 May 2019 | 4 | 1 |
| Unknown player | Injury | 19 May 2019 | 2 Jun 2019 | 14 | 2 |
 Unknown player | Muscle Injury | 4 May 2019 | 15 May 2019 | 11 | 2 |
 Unknown player | Doubtful | 28 Apr 2019 | 15 Feb 2024 | 1754 | — |
| Unknown player | Muscular Problems | 27 Apr 2019 | 12 May 2019 | 15 | 2 |
 Francisco Sierralta | Hamstring Muscle Injury | 14 Apr 2019 | 30 Apr 2019 | 16 | 3 |
| Unknown player | Calf Injury | 1 Apr 2019 | 15 Apr 2019 | 14 | 2 |
| Unknown player | Muscular Problems | 31 Mar 2019 | 13 Apr 2019 | 13 | 3 |
| Unknown player | Ankle Sprain | 30 Mar 2019 | 13 May 2019 | 44 | 7 |
| Unknown player | Sprain | 17 Mar 2019 | 26 May 2019 | 70 | 10 |
 Alessandro Bastoni | Injury | 23 Feb 2019 | 26 Feb 2019 | 3 | 1 |
 Unknown player | Ankle Sprain | 21 Feb 2019 | 2 Apr 2019 | 40 | 5 |
| Unknown player | Injury | 15 Feb 2019 | 3 Mar 2019 | 16 | 2 |
 Federico Dimarco | Injury | 8 Feb 2019 | 17 Feb 2019 | 9 | 1 |
| Unknown player | Ankle Sprain | 18 Jan 2019 | 4 Feb 2019 | 17 | 3 |
| Unknown player | Hamstring Injury | 26 Dec 2018 | 17 Jan 2019 | 22 | 2 |
| Unknown player | Doubtful | 9 Dec 2018 | 15 Feb 2024 | 1894 | — |
| Unknown player | Cruciate Ligament Tear | 4 Dec 2018 | 11 May 2019 | 158 | 21 |
| Unknown player | Muscle Injury | 3 Dec 2018 | 18 Dec 2018 | 15 | 2 |
| Unknown player | Hamstring Injury | 7 Oct 2018 | 18 Oct 2018 | 11 | 1 |
| Francisco Sierralta | Muscle Injury | 7 Oct 2018 | 31 Dec 2018 | 85 | 12 |
| Federico Dimarco | Adductor Injury | 30 Sept 2018 | 30 Dec 2018 | 91 | 12 |
