| Player | Reason | From | Until | Days | Games missed |
|---|---|---|---|---|---|
 Ruben Aguilar | COVID 19 | 26 Mar 2021 | 5 Apr 2021 | 10 | 1 |
 Sofiane Diop | Broken Hand | 24 Mar 2021 | 7 Apr 2021 | 14 | 1 |
 Unknown player | Abdominal Problems | 19 Mar 2021 | 22 Mar 2021 | 3 | 1 |
 Pietro Pellegri | Muscle Injury | 19 Feb 2021 | 31 Mar 2021 | 40 | 6 |
 Aleksandr Golovin | Thigh Problems | 13 Feb 2021 | 15 Feb 2021 | 2 | 0 |
 Willem Geubbels | Metatarsal Fracture | 9 Feb 2021 | 16 Apr 2021 | 66 | 11 |
 Unknown player | Knee Surgery | 26 Jan 2021 | 31 Mar 2021 | 64 | 11 |
| Unknown player | Knee Problems | 13 Jan 2021 | 25 Jan 2021 | 12 | 2 |
 Florentino | COVID 19 | 5 Jan 2021 | 19 Jan 2021 | 14 | 3 |
| Pietro Pellegri | Groin Problems | 3 Jan 2021 | 8 Jan 2021 | 5 | 1 |
| Pietro Pellegri | Doubtful | 20 Dec 2020 | 20 Dec 2020 | 0 | 1 |
 Cesc Fàbregas | Calf Injury | 11 Dec 2020 | 1 Feb 2021 | 52 | 8 |
| Aleksandr Golovin | Fitness | 4 Dec 2020 | 30 Dec 2020 | 26 | 5 |
 Unknown player | Doubtful | 20 Nov 2020 | 20 Nov 2020 | 0 | 1 |
| Pietro Pellegri | Injury | 13 Nov 2020 | 21 Nov 2020 | 8 | 0 |
 Unknown player | COVID 19 | 12 Nov 2020 | 23 Nov 2020 | 11 | 1 |
 Djibril Sidibé | Knock | 10 Nov 2020 | 15 Dec 2020 | 35 | 4 |
 Benjamin Lecomte | Hand Injury | 5 Nov 2020 | 31 Dec 2020 | 56 | 8 |
| Unknown player | Doubtful | 4 Oct 2020 | 4 Oct 2020 | 0 | 1 |
| Unknown player | Metatarsal Fracture | 27 Sept 2020 | 2 Nov 2020 | 36 | 4 |
| Djibril Sidibé | Knock | 20 Sept 2020 | 10 Oct 2020 | 20 | 2 |
 Unknown player | Dead Leg | 4 Sept 2020 | 14 Oct 2020 | 40 | 5 |
| Benjamin Lecomte | COVID 19 | 3 Sept 2020 | 17 Sept 2020 | 14 | 2 |
| Aleksandr Golovin | Hamstring Injury | 30 Aug 2020 | 3 Dec 2020 | 95 | 12 |
| Unknown player | Bruise On The Ankle Joint | 29 Aug 2020 | 5 Sept 2020 | 7 | 1 |
| Pietro Pellegri | Injury | 17 Aug 2020 | 27 Aug 2020 | 10 | 1 |
 Unknown player | Cruciate Ligament Tear | 15 Aug 2020 | 2 Mar 2021 | 199 | 30 |
 Unknown player | Back Problems | 16 Jul 2020 | 27 Aug 2020 | 42 | 5 |
| Cesc Fàbregas | Hamstring Injury | 15 Jul 2020 | 27 Aug 2020 | 43 | 5 |
| Pietro Pellegri | Fitness | 5 Mar 2020 | 8 Mar 2020 | 3 | 0 |
 Unknown player | Muscle Injury | 13 Jan 2020 | 4 Feb 2020 | 22 | 5 |
| Unknown player | Fitness | 30 Dec 2019 | 14 Jan 2020 | 15 | 2 |
 Benjamin Henrichs | Back Injury | 13 Dec 2019 | 29 Dec 2019 | 16 | 3 |
| Pietro Pellegri | Hamstring Injury | 22 Nov 2019 | 4 Mar 2020 | 103 | 18 |
 Keita Baldé | ILL | 8 Nov 2019 | 12 Nov 2019 | 4 | 1 |
| Cesc Fàbregas | Hamstring Injury | 30 Oct 2019 | 20 Nov 2019 | 21 | 3 |
 Unknown player | Ankle Sprain | 26 Oct 2019 | 20 Nov 2019 | 25 | 3 |
| Unknown player | Adductor Injury | 25 Oct 2019 | 6 Nov 2019 | 12 | 3 |
 Unknown player | Hamstring Injury | 1 Oct 2019 | 27 Oct 2019 | 26 | 3 |
 Unknown player | Open Wound | 24 Sept 2019 | 4 Oct 2019 | 10 | 2 |
| Unknown player | Muscle Fatigue | 19 Sept 2019 | 22 Sept 2019 | 3 | 0 |
| Unknown player | Hip Bruise | 15 Sept 2019 | 22 Sept 2019 | 7 | 1 |
| Benjamin Henrichs | Fitness | 9 Sept 2019 | 25 Sept 2019 | 16 | 2 |
| Pietro Pellegri | Torn Muscle Fiber In The Adductor Area | 29 Aug 2019 | 11 Nov 2019 | 74 | 11 |
 Unknown player | Knock | 16 Aug 2019 | 3 Sept 2019 | 18 | — |
| Benjamin Henrichs | Foot Injury | 15 Aug 2019 | 8 Sept 2019 | 24 | 3 |
 Unknown player | Fitness | 9 Aug 2019 | 18 Aug 2019 | 9 | 1 |
| Pietro Pellegri | Fitness | 2 Jun 2019 | 23 Aug 2019 | 82 | 8 |
| Willem Geubbels | Knee Surgery | 27 May 2019 | 16 Feb 2020 | 265 | 36 |
 Unknown player | Hamstring Injury | 5 May 2019 | 26 Sept 2019 | 144 | 17 |
| Unknown player | Adductor Injury | 21 Apr 2019 | 2 May 2019 | 11 | 1 |
| Unknown player | Cruciate Ligament Tear | 15 Apr 2019 | 29 Dec 2019 | 258 | 32 |
| Cesc Fàbregas | Calf Problems | 14 Apr 2019 | 15 May 2019 | 31 | 4 |
| Unknown player | Adductor Pain | 1 Apr 2019 | 10 Apr 2019 | 9 | 1 |
| Cesc Fàbregas | Thigh Problems | 9 Mar 2019 | 1 Apr 2019 | 23 | 2 |
 Unknown player | Hamstring Injury | 20 Feb 2019 | 9 May 2019 | 78 | 10 |
| Willem Geubbels | Hamstring Injury | 19 Feb 2019 | 26 May 2019 | 96 | 13 |
 Unknown player | Hip Injury | 24 Jan 2019 | 31 Jan 2019 | 7 | — |
| Unknown player | Knee Injury | 17 Jan 2019 | 25 Mar 2019 | 67 | 11 |
 Wilson Isidor | Knock | 15 Jan 2019 | 5 Apr 2019 | 80 | — |
 Unknown player | Hamstring Strain | 4 Jan 2019 | 15 Feb 2019 | 42 | 10 |
| Willem Geubbels | Hamstring Strain | 20 Dec 2018 | 7 Feb 2019 | 49 | 10 |
 Unknown player | Hamstring Strain | 20 Dec 2018 | 13 Feb 2019 | 55 | 11 |
 Unknown player | Hamstring Strain | 15 Dec 2018 | 25 Jan 2019 | 41 | 9 |
 Unknown player | Fitness | 15 Dec 2018 | 31 Dec 2018 | 16 | 3 |
| Unknown player | Hamstring Strain | 30 Nov 2018 | 17 Dec 2018 | 17 | 3 |
 Unknown player | Hamstring Strain | 22 Nov 2018 | 11 Feb 2019 | 81 | 17 |
| Djibril Sidibé | Dead Leg | 21 Nov 2018 | 15 Jan 2019 | 55 | 11 |
 Unknown player | Knock | 20 Nov 2018 | 3 Dec 2018 | 13 | 3 |
| Willem Geubbels | Hamstring Strain | 20 Nov 2018 | 17 Dec 2018 | 27 | 5 |
 Unknown player | Groin Injury | 12 Nov 2018 | 12 Mar 2019 | 120 | 22 |
 Unknown player | Groin Injury | 7 Nov 2018 | 3 Dec 2018 | 26 | 4 |
| Unknown player | Hamstring Strain | 5 Nov 2018 | 21 Dec 2018 | 46 | 9 |
| Aleksandr Golovin | Ankle Sprain | 4 Nov 2018 | 21 Nov 2018 | 17 | 2 |
 Unknown player | Foot Injury | 31 Oct 2018 | 13 Feb 2019 | 105 | 21 |
| Djibril Sidibé | Hip Injury | 25 Oct 2018 | 4 Nov 2018 | 10 | 1 |
| Unknown player | Hamstring Injury | 25 Oct 2018 | 14 Jan 2019 | 81 | 15 |
| Unknown player | Hip Problems | 20 Oct 2018 | 2 Nov 2018 | 13 | 3 |
| Unknown player | Hamstring Strain | 18 Oct 2018 | 21 Jan 2019 | 95 | 19 |
 Unknown player | Knee Injury | 14 Oct 2018 | 7 Feb 2019 | 116 | 23 |
| Pietro Pellegri | Groin Injury | 28 Sept 2018 | 1 Jun 2019 | 246 | 41 |
| Aleksandr Golovin | Fitness | 13 Sept 2018 | 19 Sept 2018 | 6 | 1 |
| Unknown player | Hamstring Strain | 10 Sept 2018 | 14 Dec 2018 | 95 | 18 |
| Pietro Pellegri | Knock | 3 Sept 2018 | 23 Sept 2018 | 20 | 3 |
| Willem Geubbels | Knee Injury | 27 Aug 2018 | 15 Nov 2018 | 80 | 14 |
| Unknown player | Calf Injury | 20 Aug 2018 | 4 Oct 2018 | 45 | 7 |
| Unknown player | Ankle Injury | 12 Aug 2018 | 18 Oct 2018 | 67 | 10 |
| Aleksandr Golovin | Ankle Sprain | 8 Aug 2018 | 20 Sept 2018 | 43 | 6 |
| Pietro Pellegri | Knock | 1 Aug 2018 | 20 Aug 2018 | 19 | 3 |
| Unknown player | Knock | 1 Aug 2018 | 3 Oct 2018 | 63 | 10 |
| Unknown player | Knock | 30 Jul 2018 | 16 Aug 2018 | 17 | 2 |
 Unknown player | Dead Leg | 26 Apr 2018 | 2 May 2018 | 6 | 1 |
 Unknown player | Bruised Knee | 21 Apr 2018 | 29 Jun 2018 | 69 | 5 |
| Djibril Sidibé | Groin Injury | 16 Apr 2018 | 10 May 2018 | 24 | 3 |
| Unknown player | Hamstring Injury | 15 Apr 2018 | 23 Apr 2018 | 8 | 2 |
| Unknown player | Hamstring Injury | 9 Apr 2018 | 16 Apr 2018 | 7 | 0 |
| Keita Baldé | Hamstring Injury | 7 Apr 2018 | 20 May 2018 | 43 | 6 |
| Unknown player | Calf Injury | 5 Apr 2018 | 11 Jun 2018 | 67 | 7 |
 Unknown player | Knee Injury | 29 Mar 2018 | 5 Apr 2018 | 7 | 1 |
| Keita Baldé | Hamstring Injury | 19 Mar 2018 | 5 Apr 2018 | 17 | 1 |
