| Player | Reason | From | Until | Days | Games missed |
|---|---|---|---|---|---|
 Unknown player | Outer Ligament Tear | 31 Mar 2016 | 27 Apr 2016 | 27 | 7 |
 Unknown player | Hamstring Injury | 17 Mar 2016 | 4 Apr 2016 | 18 | 3 |
 Unknown player | Virus | 7 Mar 2016 | 11 Mar 2016 | 4 | 0 |
 Unknown player | Ankle Injury | 15 Feb 2016 | 4 Apr 2016 | 49 | 9 |
 Unknown player | Hamstring Injury | 11 Feb 2016 | 15 Feb 2016 | 4 | 0 |
 Unknown player | Knee Injury | 8 Feb 2016 | 25 Feb 2016 | 17 | 3 |
 Unknown player | Knee Injury | 7 Feb 2016 | 1 Mar 2016 | 23 | 5 |
 Unknown player | Minor Knock | 14 Jan 2016 | 18 Jan 2016 | 4 | 0 |
 Unknown player | Hamstring Injury | 7 Jan 2016 | 28 Jan 2016 | 21 | 6 |
| Unknown player | Hamstring Injury | 7 Jan 2016 | 18 Jan 2016 | 11 | 3 |
 Unknown player | Hamstring Injury | 7 Jan 2016 | 11 Jan 2016 | 4 | 1 |
 Unknown player | Knee Surgery | 7 Jan 2016 | 4 Feb 2016 | 28 | 8 |
 Unknown player | Knee Injury | 4 Jan 2016 | 11 Jan 2016 | 7 | 2 |
 Jordan Henderson | Minor Knock | 31 Dec 2015 | 11 Jan 2016 | 11 | 3 |
| Unknown player | Torn Muscle Fiber | 28 Dec 2015 | 21 Jan 2016 | 24 | 6 |
| Unknown player | Hamstring Injury | 17 Dec 2015 | 4 Jan 2016 | 18 | 4 |
| Unknown player | Minor Knock | 14 Dec 2015 | 24 Dec 2015 | 10 | 1 |
 Unknown player | Hamstring Injury | 10 Dec 2015 | 1 Jun 2016 | 174 | 13 |
 Unknown player | Hamstring Injury | 7 Dec 2015 | 17 Jan 2016 | 41 | 9 |
| Unknown player | Hamstring Strain | 23 Nov 2015 | 10 Dec 2015 | 17 | 4 |
| Unknown player | Inner Knee Ligament Tear | 9 Nov 2015 | 17 Dec 2015 | 38 | 7 |
| Unknown player | Hamstring Injury | 5 Nov 2015 | 19 Nov 2015 | 14 | 2 |
| Unknown player | Edema In The Knee | 16 Oct 2015 | 10 Nov 2015 | 25 | 7 |
| Unknown player | Torn Muscle Fiber | 15 Oct 2015 | 3 Dec 2015 | 49 | 4 |
 Unknown player | Cruciate Ligament Tear | 15 Oct 2015 | 12 May 2016 | 210 | 49 |
 Joe Gomez | Cruciate Ligament Tear | 12 Oct 2015 | 22 May 2016 | 223 | 52 |
| Unknown player | Back Injury | 24 Sept 2015 | 19 Oct 2015 | 25 | 4 |
| Unknown player | Ankle Sprain | 24 Sept 2015 | 26 Oct 2015 | 32 | 6 |
| Unknown player | Thigh Problems | 21 Sept 2015 | 22 Oct 2015 | 31 | 5 |
| Jordan Henderson | Metatarsal Fracture | 17 Sept 2015 | 26 Nov 2015 | 70 | 14 |
| Jordan Henderson | Heel Injury | 17 Aug 2015 | 17 Sept 2015 | 31 | 6 |
| Unknown player | Thigh Problems | 3 Aug 2015 | 17 Sept 2015 | 45 | 8 |
 Unknown player | Foot Injury | 1 May 2015 | 11 May 2015 | 10 | 2 |
| Unknown player | Cartilage Damage | 27 Apr 2015 | 11 Jan 2016 | 259 | 39 |
| Unknown player | Groin Problems | 16 Apr 2015 | 30 Apr 2015 | 14 | 3 |
| Unknown player | Hamstring Injury | 9 Apr 2015 | 25 May 2015 | 46 | 7 |
| Unknown player | Hip Injury | 8 Apr 2015 | 22 Sept 2015 | 167 | 19 |
| Unknown player | Knee Problems | 3 Apr 2015 | 7 Apr 2015 | 4 | 1 |
| Unknown player | Hip Injury | 19 Feb 2015 | 5 Mar 2015 | 14 | 4 |
| Unknown player | Groin Injury | 9 Feb 2015 | 19 Mar 2015 | 38 | 9 |
 Unknown player | Ankle Injury | 8 Feb 2015 | 19 Feb 2015 | 11 | 2 |
 Unknown player | Hamstring Injury | 26 Dec 2014 | 13 Mar 2015 | 77 | 20 |
| Unknown player | Knock | 18 Dec 2014 | 15 Jan 2015 | 28 | 6 |
| Unknown player | Groin Injury | 18 Dec 2014 | 1 Jan 2015 | 14 | 3 |
| Unknown player | Hamstring Injury | 18 Nov 2014 | 28 Jan 2015 | 71 | 18 |
| Unknown player | Hamstring Injury | 13 Nov 2014 | 8 Dec 2014 | 25 | 5 |
 Unknown player | Groin Injury | 1 Oct 2014 | 1 Dec 2014 | 61 | 12 |
| Unknown player | Hamstring Injury | 29 Sept 2014 | 15 Dec 2014 | 77 | 15 |
| Unknown player | Groin Injury | 18 Sept 2014 | 25 Sept 2014 | 7 | 2 |
| Unknown player | Knee Problems | 11 Sept 2014 | 13 Oct 2014 | 32 | 7 |
 Emre Can | Ankle Injury | 8 Sept 2014 | 16 Oct 2014 | 38 | 7 |
| Unknown player | Hamstring Strain | 5 Sept 2014 | 3 Oct 2014 | 28 | 6 |
| Unknown player | Edema In The Knee | 31 Jul 2014 | 16 Apr 2015 | 259 | 52 |
| Unknown player | Cruciate Ligament Injury | 20 Jan 2014 | 27 Feb 2014 | 38 | 7 |
| Unknown player | Hamstring Strain | 30 Dec 2013 | 27 Feb 2014 | 59 | 11 |
| Unknown player | Ankle Sprain | 3 Dec 2013 | 8 Jan 2014 | 36 | 8 |
| Unknown player | Groin Injury | 28 Nov 2013 | 16 Jan 2014 | 49 | 10 |
| Unknown player | Torn Lateral Ankle Ligament | 27 Nov 2013 | 8 Jan 2014 | 42 | 9 |
 Iago Aspas | Hamstring Strain | 18 Oct 2013 | 28 Nov 2013 | 41 | 5 |
| Unknown player | Shoulder Injury | 16 Sept 2013 | 31 Oct 2013 | 45 | 7 |
 Unknown player | Ankle Injury | 27 Aug 2013 | 5 Oct 2013 | 39 | 7 |
| Unknown player | Hamstring Strain | 26 Aug 2013 | 16 Sept 2013 | 21 | 3 |
 Unknown player | Cruciate Ligament Tear | 15 Aug 2013 | 20 Feb 2014 | 189 | 33 |
| Unknown player | Hip Injury | 3 Apr 2013 | 12 Jul 2013 | 100 | 7 |
| Unknown player | Shoulder Injury | 18 Mar 2013 | 1 Jul 2013 | 105 | 8 |
 Unknown player | Shoulder Injury | 17 Feb 2013 | 27 Apr 2013 | 69 | 9 |
| Unknown player | Groin Problems | 5 Feb 2013 | 13 Feb 2013 | 8 | 1 |
 Unknown player | Broken Nose Bone | 14 Jan 2013 | 28 Jan 2013 | 14 | 1 |
| Unknown player | Knock | 17 Dec 2012 | 4 Feb 2013 | 49 | 10 |
| Unknown player | Back Problems | 22 Oct 2012 | 12 Nov 2012 | 21 | 5 |
| Unknown player | Metatarsal Fracture | 11 Oct 2012 | 13 Jan 2013 | 94 | 20 |
 Unknown player | Cruciate Ligament Tear | 23 Sept 2012 | 1 May 2013 | 220 | 42 |
| Unknown player | Hamstring Injury | 27 Aug 2012 | 29 Nov 2012 | 94 | 20 |
| Unknown player | Thigh Problems | 21 Mar 2012 | 14 Apr 2012 | 24 | 5 |
 Unknown player | Cruciate Ligament Injury | 20 Mar 2012 | 15 Jun 2012 | 87 | 12 |
 Unknown player | Strain In The Thigh And Gluteal Muscles | 11 Jan 2012 | 25 Jan 2012 | 14 | 3 |
| Unknown player | Cruciate Ligament Tear | 1 Dec 2011 | 14 Jun 2012 | 196 | 33 |
 Unknown player | Ankle Injury | 16 Oct 2011 | 26 Apr 2012 | 193 | 35 |
 Unknown player | Adductor Injury | 22 May 2011 | 5 Jun 2011 | 14 | 1 |
| Unknown player | Thigh Problems | 27 Feb 2011 | 10 Jun 2011 | 103 | 13 |
| Unknown player | Foot Injury | 3 Feb 2011 | 24 Feb 2011 | 21 | 3 |
 Unknown player | Knee Injury | 11 Dec 2010 | 7 Jan 2011 | 27 | 5 |
| Unknown player | Broken Ankle | 19 Nov 2010 | 1 Jan 2011 | 43 | 7 |
 Unknown player | Ankle Injury | 16 Oct 2008 | 23 Oct 2008 | 7 | 2 |
