| Player | Reason | From | Until | Days | Games missed |
|---|---|---|---|---|---|
Unknown player | Knee Problems | 23 Oct 2021 | 2 Nov 2021 | 10 | 3 |
 Caoimhín Kelleher | ILL | 22 Oct 2021 | 1 Nov 2021 | 10 | 3 |
 Curtis Jones | Groin Injury | 12 Oct 2021 | 21 Oct 2021 | 9 | 2 |
 Trent Alexander-Arnold | Muscular Problems | 27 Sept 2021 | 14 Oct 2021 | 17 | 2 |
Unknown player | Calf Injury | 18 Sept 2021 | 31 Oct 2021 | 43 | 9 |
| Trent Alexander-Arnold | ILL | 18 Sept 2021 | 20 Sept 2021 | 2 | 1 |
 Harvey Elliott | Dislocation Fracture Of The Ankle Joint | 13 Sept 2021 | 31 Jan 2022 | 140 | 30 |
 Takumi Minamino | Thigh Problems | 4 Sept 2021 | 13 Sept 2021 | 9 | 0 |
Unknown player | Muscle Injury | 29 Aug 2021 | 22 Sept 2021 | 24 | 3 |
Unknown player | Muscle Injury | 15 Aug 2021 | 8 Sept 2021 | 24 | 2 |
 Andrew Robertson | Ankle Injury | 8 Aug 2021 | 18 Aug 2021 | 10 | 3 |
Unknown player | Foot Injury | 13 May 2021 | 24 May 2021 | 11 | 3 |
Unknown player | Knock | 8 May 2021 | 31 May 2021 | 23 | 5 |
 Ozan Kabak | Muscle Injury | 3 May 2021 | 27 May 2021 | 24 | 5 |
Unknown player | Injury | 2 May 2021 | 17 May 2021 | 15 | 2 |
Unknown player | Knee Injury | 5 Mar 2021 | 1 Apr 2021 | 27 | 3 |
 Jordan Henderson | Groin Surgery | 26 Feb 2021 | 19 May 2021 | 82 | 14 |
Unknown player | Muscle Injury | 11 Feb 2021 | 1 Mar 2021 | 18 | 3 |
 Alisson | ILL | 1 Feb 2021 | 5 Feb 2021 | 4 | 1 |
Unknown player | Knock | 30 Jan 2021 | 6 Feb 2021 | 7 | 2 |
Unknown player | Ankle Injury | 28 Jan 2021 | 1 Jul 2021 | 154 | 23 |
Unknown player | Muscular Problems | 26 Jan 2021 | 6 Feb 2021 | 11 | 3 |
Unknown player | Doubtful | 30 Dec 2020 | 30 Dec 2020 | 0 | 1 |
Unknown player | Groin Problems | 28 Dec 2020 | 21 Jan 2021 | 24 | 4 |
Unknown player | Ankle Injury | 20 Dec 2020 | 18 Feb 2021 | 60 | 13 |
Unknown player | Doubtful | 19 Dec 2020 | 19 Dec 2020 | 0 | 1 |
Unknown player | Doubtful | 16 Dec 2020 | 16 Dec 2020 | 0 | 1 |
Unknown player | Back Problems | 14 Dec 2020 | 17 Dec 2020 | 3 | 0 |
Unknown player | Cruciate Ligament Injury | 10 Dec 2020 | 15 Dec 2020 | 5 | 1 |
 Konstantinos Tsimikas | Knee Injury | 10 Dec 2020 | 20 Jan 2021 | 41 | 8 |
Unknown player | Knee Bruise | 7 Dec 2020 | 1 Mar 2021 | 84 | 18 |
| Alisson | Hip Injury | 29 Nov 2020 | 12 Dec 2020 | 13 | 3 |
Unknown player | Hamstring Injury | 28 Nov 2020 | 26 Dec 2020 | 28 | 7 |
Unknown player | Hamstring Injury | 23 Nov 2020 | 5 Dec 2020 | 12 | 3 |
Unknown player | Doubtful | 22 Nov 2020 | 22 Nov 2020 | 0 | 1 |
| Jordan Henderson | Knock | 16 Nov 2020 | 27 Nov 2020 | 11 | 2 |
Unknown player | Muscle Injury | 16 Nov 2020 | 26 Dec 2020 | 40 | 9 |
Unknown player | Groin Injury | 15 Nov 2020 | 24 Nov 2020 | 9 | 1 |
Unknown player | COVID 19 | 13 Nov 2020 | 24 Nov 2020 | 11 | 1 |
 Joe Gomez | Patellar Tendon Problems | 11 Nov 2020 | 30 Jun 2021 | 231 | 39 |
| Trent Alexander-Arnold | Calf Injury | 9 Nov 2020 | 7 Dec 2020 | 28 | 4 |
 Neco Williams | ILL | 7 Nov 2020 | 9 Nov 2020 | 2 | 0 |
Unknown player | Hamstring Injury | 27 Oct 2020 | 21 Nov 2020 | 25 | 4 |
Unknown player | Bruise | 19 Oct 2020 | 2 Nov 2020 | 14 | 4 |
 Virgil van Dijk | Cruciate Ligament Tear | 19 Oct 2020 | 30 Jun 2021 | 254 | 45 |
Unknown player | Knee Injury | 17 Oct 2020 | 28 Dec 2020 | 72 | 16 |
Unknown player | COVID 19 | 14 Oct 2020 | 3 Nov 2020 | 20 | 5 |
| Alisson | Shoulder Injury | 3 Oct 2020 | 23 Oct 2020 | 20 | 3 |
Unknown player | COVID 19 | 2 Oct 2020 | 16 Oct 2020 | 14 | 1 |
Unknown player | Doubtful | 28 Sept 2020 | 28 Sept 2020 | 0 | 1 |
| Konstantinos Tsimikas | Thigh Problems | 25 Sept 2020 | 3 Nov 2020 | 39 | 8 |
Unknown player | COVID 19 | 23 Sept 2020 | 16 Oct 2020 | 23 | 4 |
| Alisson | ILL | 21 Sept 2020 | 27 Sept 2020 | 6 | 1 |
Unknown player | Calf Injury | 21 Sept 2020 | 27 Sept 2020 | 6 | 1 |
| Joe Gomez | Minor Knock | 17 Sept 2020 | 26 Sept 2020 | 9 | 2 |
Unknown player | Thigh Problems | 14 Sept 2020 | 15 Oct 2020 | 31 | 5 |
| Neco Williams | Quarantine | 12 Sept 2020 | 20 Sept 2020 | 8 | 1 |
| Konstantinos Tsimikas | Quarantine | 4 Sept 2020 | 19 Sept 2020 | 15 | 2 |
Unknown player | Knee Injury | 21 Aug 2020 | 12 Dec 2020 | 113 | 23 |
| Neco Williams | ILL | 21 Jul 2020 | 23 Jul 2020 | 2 | 0 |
| Jordan Henderson | Knee Injury | 9 Jul 2020 | 30 Aug 2020 | 52 | 6 |
Unknown player | Hamstring Strain | 9 Jul 2020 | 21 Jul 2020 | 12 | 2 |
Unknown player | Knock | 2 Jul 2020 | 10 Jul 2020 | 8 | 3 |
Unknown player | Ankle Injury | 22 Jun 2020 | 30 Jul 2020 | 38 | 8 |
Unknown player | Hamstring Injury | 22 Jun 2020 | 30 Jun 2020 | 8 | 1 |
| Andrew Robertson | Minor Knock | 15 Jun 2020 | 22 Jun 2020 | 7 | 1 |
Unknown player | ILL | 10 Mar 2020 | 12 Mar 2020 | 2 | 0 |
| Andrew Robertson | Rest | 5 Mar 2020 | 9 Mar 2020 | 4 | 1 |
| Alisson | Hip Injury | 1 Mar 2020 | 20 May 2020 | 80 | 3 |
Unknown player | Groin Injury | 1 Mar 2020 | 6 Mar 2020 | 5 | 1 |
| Joe Gomez | Rest | 27 Feb 2020 | 1 Mar 2020 | 3 | 1 |
Unknown player | Angina | 26 Feb 2020 | 3 Mar 2020 | 6 | 1 |
| Neco Williams | Fitness | 24 Feb 2020 | 29 Feb 2020 | 5 | 1 |
Unknown player | Hamstring Injury | 19 Feb 2020 | 2 Mar 2020 | 12 | 2 |
| Jordan Henderson | Hamstring Injury | 19 Feb 2020 | 10 Mar 2020 | 20 | 4 |
| Neco Williams | ILL | 29 Jan 2020 | 1 Feb 2020 | 3 | 1 |
Unknown player | Hamstring Injury | 26 Jan 2020 | 11 Feb 2020 | 16 | 4 |
Unknown player | Muscle Injury | 24 Jan 2020 | 14 Feb 2020 | 21 | 4 |
| Neco Williams | Fitness | 18 Jan 2020 | 20 Jan 2020 | 2 | 0 |
Unknown player | Calf Injury | 12 Jan 2020 | 4 Jul 2020 | 174 | 16 |
Unknown player | Hip Injury | 6 Jan 2020 | 14 Feb 2020 | 39 | 7 |
Unknown player | Groin Problems | 2 Jan 2020 | 25 Jan 2020 | 23 | 5 |
Unknown player | Hamstring Strain | 28 Dec 2019 | 10 Jan 2020 | 13 | 3 |
Unknown player | Ankle Injury | 23 Dec 2019 | 4 Jan 2020 | 12 | 3 |
| Virgil van Dijk | ILL | 16 Dec 2019 | 19 Dec 2019 | 3 | 1 |
Unknown player | Muscle Injury | 13 Dec 2019 | 24 Jan 2020 | 42 | 10 |
Unknown player | Knock | 12 Dec 2019 | 23 Dec 2019 | 11 | 4 |
Unknown player | Ankle Injury | 28 Nov 2019 | 18 Jan 2020 | 51 | 13 |
Unknown player | ILL | 26 Nov 2019 | 28 Nov 2019 | 2 | 0 |
Unknown player | Ankle Injury | 20 Nov 2019 | 4 Jan 2020 | 45 | 0 |
Unknown player | Knee Injury | 28 Oct 2019 | 16 Jan 2020 | 80 | 19 |
| Trent Alexander-Arnold | ILL | 21 Oct 2019 | 28 Oct 2019 | 7 | 1 |
Unknown player | Ankle Problems | 6 Oct 2019 | 22 Oct 2019 | 16 | 1 |
Unknown player | Head Injury | 3 Oct 2019 | 7 Oct 2019 | 4 | 1 |
Unknown player | Calf Injury | 23 Sept 2019 | 26 Nov 2019 | 64 | 12 |
Unknown player | Hamstring Strain | 23 Sept 2019 | 27 Sept 2019 | 4 | 1 |
Unknown player | Torn Muscle Bundle | 22 Sept 2019 | 28 Sept 2019 | 6 | 2 |
Unknown player | Ankle Injury | 15 Sept 2019 | 27 Sept 2019 | 12 | 3 |
Unknown player | ILL | 11 Aug 2019 | 30 Aug 2019 | 19 | 3 |
Unknown player | Torn Muscle Bundle | 10 Aug 2019 | 24 Sept 2019 | 45 | 7 |
